Results 121 to 130 of about 673,559 (305)
Advanced Science, EarlyView.An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng +9 more
wiley +1 more source
Widespread Misinterpretable ChIP-seq Bias in Yeast
PLoS ONE, 2013 Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is widely used to detect genome-wide interactions between a protein of interest and DNA in vivo. Loci showing strong enrichment over adjacent background regions are typically considered to be sites of binding.
Park, Daechan +3 more
openaire +5 more sources
ChIP-Seq analysis reveals direct ETS1 targets and their epigenomic features in SCC25 cells.
, 2019 (A) Heatmap of the ChIP-Seq signal at the IDR-generated consensus ETS1 binding sites across three ChIP replicates. The individual ChIP-Signal matrices were subjected to hierarchical clustering and presented as a dendrogram (B) The top de novo motif ...
Maria Tsompana (3037167) +6 more
core +1 more source
005-A0IgG-normRPKM.bwOsteo-mm9 ChIP-seq bw
, 2020 oseto mm9 Chip-seq ...
su pin koh (6728891)
core +1 more source
Advanced Science, EarlyView.A flexible pressure sensor with triple‐gradient design of conductivity, modulus, and dimension in binary micro‐dome pixels is proposed. Based on precisely‐designed CNT/PDMS matrix, the device exhibits a linear sensitivity of 974.1 kPa−1 across range up to 1.8 MPa (R2 > 0.99), offering an effective strategy for potential applications in healthcare ...
Yifan Liu +9 more
wiley +1 more source
007-A1IgG-normRPKM.bwOsteo-mm9 ChIP-seq bw
, 2020 oseto mm9 Chip-seq ...
su pin koh (6728891)
core +1 more source
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
Populus transcription factor ChIP-seq
, 2015 Using ChIP-seq to identify transcription factors genome-wide binding ...
USDA (17854931)
core
W-ChIPeaks: a comprehensive web application tool for processing ChIP-chip and ChIP-seq data
, 2010 Summary: ChIP-based technology is becoming the leading technology to globally profile thousands of transcription factors and elucidate the transcriptional regulation mechanisms in living cells.
Victor X Jin +4 more
core +1 more source