Results 31 to 40 of about 604,881 (306)
An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition. [PDF]
PLoS ONE, 2016 Chromatin immunoprecipitation and DNA sequencing (ChIP-seq) has been instrumental in inferring the roles of histone post-translational modifications in the regulation of transcription, chromatin compaction and other cellular processes that require ...
Brian Egan +16 more
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Prediction accuracy of regulatory elements from sequence varies by functional sequencing technique
Frontiers in Cellular and Infection Microbiology, 2023 IntroductionVarious sequencing based approaches are used to identify and characterize the activities of cis-regulatory elements in a genome-wide fashion.
Ronald J. Nowling +3 more
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intePareto: an R package for integrative analyses of RNA-Seq and ChIP-Seq data
BMC Genomics, 2020 Background RNA-Seq, the high-throughput sequencing (HT-Seq) of mRNAs, has become an essential tool for characterizing gene expression differences between different cell types and conditions.
Yingying Cao +2 more
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Computational methodology for ChIP‐seq analysis [PDF]
Quantitative Biology, 2013 Chromatin immunoprecipitation coupled with massive parallel sequencing (ChIP‐seq) is a powerful technology to identify the genome‐wide locations of DNA binding proteins such as transcription factors or modified histones. As more and more experimental laboratories are adopting ChIP‐seq to unravel the transcriptional and epigenetic regulatory mechanisms,
Hyunjin Shin +4 more
openaire +2 more sources
Genomic location analysis by ChIP‐Seq [PDF]
Journal of Cellular Biochemistry, 2009 AbstractThe interaction of a multitude of transcription factors and other chromatin proteins with the genome can influence gene expression and subsequently cell differentiation and function. Thus systematic identification of binding targets of transcription factors is key to unraveling gene regulation networks.
Artem, Barski, Keji, Zhao
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ChIP-Seq analysis of the recruitment of Nurr1 and histone modifiers to the HIV provirus.
, 2022 Histograms show numbers of sequence reads on the Y axis along the length of the reporter HIV-1 pro-viral genome on the X axis. A, Aligned reporter genome. B, Nurr1 (Santa Cruz Biotech, Cat #sc-81345). C, CoREST (Cell Signaling, Cat #14567.
David Alvarez-Carbonell (3721597) +7 more
core +1 more source
Imputation for transcription factor binding predictions based on deep learning. [PDF]
PLoS Computational Biology, 2017 Understanding the cell-specific binding patterns of transcription factors (TFs) is fundamental to studying gene regulatory networks in biological systems, for which ChIP-seq not only provides valuable data but is also considered as the gold standard ...
Qian Qin, Jianxing Feng
doaj +1 more source
CSA: a web service for the complete process of ChIP-Seq analysis
BMC Bioinformatics, 2019 Background Chromatin immunoprecipitation sequencing (ChIP-seq) is a technology that combines chromatin immunoprecipitation (ChIP) with next generation of sequencing technology (NGS) to analyze protein interactions with DNA.
Min Li +4 more
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PICS: Probabilistic Inference for ChIP-seq [PDF]
Biometrics, 2010 ChIP-seq, which combines chromatin immunoprecipitation with massively parallel short-read sequencing, can profile in vivo genome-wide transcription factor-DNA association with higher sensitivity, specificity and spatial resolution than ChIP-chip. While it presents new opportunities for research, ChIP-seq poses new challenges for statistical analysis ...
Zhang, Xuekui +6 more
openaire +4 more sources
, 2022 A) Log2 immunoprecipitate/Input ChIP-seq data from each replicate (2x AP2-EXP::GFP and 1xAP2-EXP::HA) of AP2-EXP ChIP-seq visualized by IGV at a representative DNA locus.
Charisse Flerida A. Pasaje (13949382) +13 more
core +1 more source