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Cold Spring Harbor Protocols, 2018
ChIP-chip can be used to analyze protein–DNA interactions in a region-wide and genome-wide manner. DNA microarrays contain PCR products or oligonucleotide probes that are designed to represent genomic sequences. Identification of genomic sites that interact with a specific protein is based on competitive hybridization of the ChIP-enriched DNA and the ...
Kim, Tae Hoon, Dekker, Job
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ChIP-chip can be used to analyze protein–DNA interactions in a region-wide and genome-wide manner. DNA microarrays contain PCR products or oligonucleotide probes that are designed to represent genomic sequences. Identification of genomic sites that interact with a specific protein is based on competitive hybridization of the ChIP-enriched DNA and the ...
Kim, Tae Hoon, Dekker, Job
openaire +3 more sources
Cold Spring Harbor Protocols, 2018
ChIP is a powerful method for analyzing protein–DNA interactions that occur in vivo. A basic protocol involves immunoprecipitation of the cross-linked nucleoprotein complex and isolating and analyzing the DNA that is associated with the protein of interest.
Kim, Tae Hoon, Dekker, Job
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ChIP is a powerful method for analyzing protein–DNA interactions that occur in vivo. A basic protocol involves immunoprecipitation of the cross-linked nucleoprotein complex and isolating and analyzing the DNA that is associated with the protein of interest.
Kim, Tae Hoon, Dekker, Job
openaire +3 more sources
All Things ChIP: ChIP-Chip, ChIP-Seq, ChIP-PCR
2011Chromatin immunoprecipitation (ChIP) has long been a valuable tool for scientists seeking to study in vivo protein–DNA interactions. Beginning with the pioneering efforts of Solomon et al., successful applications of the ChIP protocol have spanned multiple model systems across a wide breadth of biological disciplines.
Jason M. Rizzo, Michael J. Buck
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Epigenetic Analysis: ChIP-chip and ChIP-seq
2011The access of transcription factors and the replication machinery to DNA is regulated by the epigenetic state of chromatin. In eukaryotes, this complex layer of regulatory processes includes the direct methylation of DNA, as well as covalent modifications to histones. Using next-generation sequencers, it is now possible to obtain profiles of epigenetic
Pellegrini M, Ferrari R
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Chromatin Immunoprecipitation for ChIP-chip and ChIP-seq
2014Bacterial adaptation to given environmental conditions is largely achieved by complex gene regulatory processes. To address the question how and to what extend single transcriptional regulators modulate gene expression, chromatin immunoprecipitation (ChIP) coupled to DNA microarrays (ChIP-chip) or to next-generation sequencing (ChIP-seq) is one of the ...
Sebastian Schulz, Susanne Häussler
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1990
Wie komplex das Gehirn auch sein mag, das Elektroenzephalogramm (EEG), Ausdruck der elektrischen Aktivitat von hundert Milliarden Nervenzellen, scheint uns etwas uber seine geistig-seelische Tatigkeit zu offenbaren. Schon Hans Berger, der Entdecker des EEG, beobachtete, das die Alpha-Wellen beim Schliesen der Augen merklich zuruckgehen: Sie sind also ...
Ernst Hunziker, Guerino Mazzola
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Wie komplex das Gehirn auch sein mag, das Elektroenzephalogramm (EEG), Ausdruck der elektrischen Aktivitat von hundert Milliarden Nervenzellen, scheint uns etwas uber seine geistig-seelische Tatigkeit zu offenbaren. Schon Hans Berger, der Entdecker des EEG, beobachtete, das die Alpha-Wellen beim Schliesen der Augen merklich zuruckgehen: Sie sind also ...
Ernst Hunziker, Guerino Mazzola
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Chip-to-Chip and Chip-to-Wafer Thermocompression Flip Chip Bonding
2016 IEEE 66th Electronic Components and Technology Conference (ECTC), 2016Adoption of Chip-to-Chip (C2C) and Chip-to-Wafer (C2W) thermocompression (TC) flip-chip (FC) bonding in high volume manufacturing of advanced memory modules is accelerating. Advanced memory modules in the form of Wide I/O2, High Bandwidth Memory (HBM) and Hybrid Memory Cubes (HMC) use Through-Silicon Vias (TSVs) and copper pillars to achieve ultra ...
Horst Clauberg +5 more
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