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ChIP-chip

Cold Spring Harbor Protocols, 2018
ChIP-chip can be used to analyze protein–DNA interactions in a region-wide and genome-wide manner. DNA microarrays contain PCR products or oligonucleotide probes that are designed to represent genomic sequences. Identification of genomic sites that interact with a specific protein is based on competitive hybridization of the ChIP-enriched DNA and the ...
Kim, Tae Hoon, Dekker, Job
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Epigenetic Analysis: ChIP-chip and ChIP-seq

2011
The access of transcription factors and the replication machinery to DNA is regulated by the epigenetic state of chromatin. In eukaryotes, this complex layer of regulatory processes includes the direct methylation of DNA, as well as covalent modifications to histones. Using next-generation sequencers, it is now possible to obtain profiles of epigenetic
Pellegrini M, Ferrari R
openaire   +4 more sources

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