Results 261 to 270 of about 1,488,806 (302)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Protocol to extract and sort GFP-tagged nuclei from lung adenocarcinoma tissue in genetically engineered mouse models. [PDF]

STAR Protoc
Gillis K, Orellana WA, Snyder EL.
europepmc   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

The development and validation of a genotyping-by-target sequencing chip for fungal population genetic analysis. [PDF]

Stress Biol
Yan H, Ma Z, Yao Q, Cao S, Jia Q, Li J, Zhao J, Yan W, Ma J, Chen W, Zhang B, Ma X, Wang X, Han D, Kang Z, Huang L, Zeng Q.   +16 more
europepmc   +1 more source

Teenagers’ response to self- and other-directed anti-smoking messages: a cross-cultural study. [PDF]

Foubert, Bram, Miller, Chip, Reardon, James, Vida, Irena   +3 more
core   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

A CRISPR-assisted passive microfluidic chip for rapid, visual detection of multiple respiratory viruses. [PDF]

Sci Rep
Li X, Guo J, Yang H, Wu Y, Xie Z, Li D.
europepmc   +1 more source

A Comparative Analysis of Plasmonic and Dielectric Metasurface Sensing Platforms Powered by Bound States in the Continuum

Advanced Functional Materials, EarlyView.
This work reveals a fundamental trade‐off between plasmonic and dielectric metasurfaces for molecular sensing. A clear performance crossover is identified: dielectric metasurfaces excel in air, while plasmonic metasurfaces dominate in lossy solvents. These results establish design rules for infrared metasurface sensors and enable optimized performance ...
Tao Jiang, Angana Bhattacharya, Martin Barkey, Andreas Aigner, Lina Rohrer, Thomas Weber, Juan Wang, Stefan A. Maier, Andreas Tittl   +8 more
wiley   +1 more source

An Effective Hybrid Rescheduling Method for Wafer Chip Precision Packaging Workshops in Complex Manufacturing Environments. [PDF]

Micromachines (Basel)
Wang Z, Fang W, Yang Y.
europepmc   +1 more source

A Five-Electrode Contactless Conductivity Detector Based on a Sandwiched Microfluidic Chip for Miniaturized Ion Chromatography. [PDF]

Sensors (Basel)
Chen K, Zhang R, Wang M, Wang B, Wang S, Zhao H.   +5 more
europepmc   +1 more source