Results 51 to 60 of about 1,453,160 (348)
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
FEBS Letters, EarlyView.Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source
Development of micro sampling nozzle for closed tube
Nihon Kikai Gakkai ronbunshu, 2017 In a biochemical automatic analyzer, generally it is necessary to open the cap of the sample tube before the analysis. Users of the analyzer demand a closed tube sampling (CTS) function to reduce the workload and the infection risk.
Yosuke HORIE, Takamichi MORI
doaj +1 more source
Cascaded feature enhancement network model for real-time video monitoring of power system
Energy Reports, 2021 The application of real-time monitoring has been widely used to detect the safety and stability of the electric power system. Traditional monitoring relies heavily on human judgment and is impossible to detect status in real-time.
Xitian Long +6 more
doaj +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Recycling Chips of Stainless Steel Using a Full Factorial Design
Metals, 2019 The aim of this study was to provide an experimental investigation on the novel method for recycling chips of duplex stainless steel, with the addition of vanadium carbide, in order to produce metal/carbide composites from a high-energy mechanical ...
Claudiney Mendonça +8 more
doaj +1 more source
Dianzi Jishu Yingyong, 2023 At present, in chip design companies, sample verification is carried out for mass production chips. Most of the traditional sample verification methods design corresponding test equipment based on the characteristics of the chip, and then test the chip ...
Xu Jinglin +5 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Using CisGenome to Analyze ChIP‐chip and ChIP‐seq Data [PDF]
Current Protocols in Bioinformatics, 2011 AbstractChromatin immunoprecipitation (ChIP) coupled with genome tiling array hybridization (ChIP‐chip) and ChIP followed by massively parallel sequencing (ChIP‐seq) are high‐throughput approaches to profiling genome‐wide protein‐DNA interactions.
Hui Jiang +3 more
openaire +3 more sources
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source