Results 51 to 60 of about 1,488,806 (302)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Identification E-SIM For Motorcycle Security Using Atmega 8 Microcontroller

open access: yesJurnal Riset Informatika, 2022
Motorcycle theft is getting more disturbing, so it encourages the author to make security devices on motorbikes. This study has created a security system that can secure motorcycles using an e-SIM based on the Atmega-8 Microcontroller.
Hafdiarsya Saiyar, Desmulyati Desmulyati
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Seebeck-driven transverse thermoelectric generation in on-chip devices [PDF]

open access: green, 2022
Weinan Zhou   +3 more
openalex   +1 more source

Multichip packaging with thermal insulation [PDF]

open access: yes, 1968
Thermal insulation technique permits low and high power electronic chips to operate in the same package without thermal cross-coupling. An alumina glass shield thermally isolates the low power chip from the high power chip while Kovar substrate acts as a
Mc Inturff, R. G., Mend, W. G.
core   +1 more source

Optimizing Event Selection with the Random Grid Search

open access: yes, 2018
The random grid search (RGS) is a simple, but efficient, stochastic algorithm to find optimal cuts that was developed in the context of the search for the top quark at Fermilab in the mid-1990s.
Bhat, Pushpalatha C.   +3 more
core   +1 more source

VCSEL intrinsic response extraction using T-Matrix formalism [PDF]

open access: yes, 2009
We present a new method to remove the parasitics contribution to the VCSEL chip response, in order to obtain the intrinsic S21 behavior. The on-chip VCSEL is defined as two cascaded two-port subsystems representing the electrical access and the VCSEL ...
Bacou, Alexandre   +6 more
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Maintaining public health insurance benefits: How primary care clinics help keep low-income patients insured

open access: yesPatient Experience Journal, 2017
Low-income families struggle to obtain and maintain public health insurance. We identified strategies used by Community Health Centers (CHCs) to assist patients with insurance applications, and assessed patients’ receptivity to these efforts ...
Rose Harding   +9 more
doaj  

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