Results 51 to 60 of about 639,557 (319)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

CARM: congestion adaptive routing method for on chip networks [PDF]

open access: yes, 2014
Network-on-Chip (NoC) has emerged as a long-term and efficient on-chip communication solution for MC-SoC and CMP micro-architectures to overcome bottleneck of traditional bus-based interconnects.
Laxmi, V.   +9 more
core   +1 more source

Electronic Chips Acting as Capacitors or Inductors when Laser Act as Information Transmitter

open access: yesEast European Journal of Physics, 2022
To increase the speed of information flow and storage capacity in electronic devices laser can be used to carry information instead of electric current.
Mashair Ahmed Mohammed Yousef   +3 more
doaj   +1 more source

CoCAS: a ChIP-on-chip analysis suite [PDF]

open access: yesBioinformatics, 2009
Abstract Motivation: High-density tiling microarrays are increasingly used in combination with ChIP assays to study transcriptional regulation. To ease the analysis of the large amounts of data generated by this approach, we have developed ChIP-on-chip Analysis Suite (CoCAS), a standalone software suite which implements optimized ChIP-on-
Touati Benoukraf   +10 more
openaire   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Adaptable Switch boxes as on-chip routing nodes for networks-on-chip

open access: yes, 2005
Eickhoff R, Niemann J-C, Porrmann M, Rückert U. Adaptable Switch boxes as on-chip routing nodes for networks-on-chip. In: Rettberg A, Zanella MC, Rammig FJ, eds. From Specification to Embedded Systems Application .
Eickhoff, Ralf   +6 more
core   +1 more source

Development of Intelligent Identification of Cutting States by Spectrum Analysis for CNC Turning

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2008
In order to realize the intelligent machine tools, which can autonomously determine the cutting states and can change them automatically as required due to changes in the environmental conditions, an in-process monitoring and identification of cutting ...
Somkiat TANGJITSITCHAROEN
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

A new material model for 2D numerical simulation of serrated chip formation when machining titanium alloy Ti-6Al-4V [PDF]

open access: yes, 2008
A new material constitutive law is implemented in a 2D finite element model to analyse the chip formation and shear localisation when machining titanium alloys. The numerical simulations use a commercial finite element software (FORGE 2005) able to solve
CALAMAZ, Madalina   +2 more
core   +1 more source

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