Results 291 to 300 of about 802,912 (335)

ERP organ-function on a chip in 2017

open access: green, 2018
R. Hanemaaijer   +3 more
openalex   +1 more source

ChIP-chip

Cold Spring Harbor Protocols, 2018
ChIP-chip can be used to analyze protein–DNA interactions in a region-wide and genome-wide manner. DNA microarrays contain PCR products or oligonucleotide probes that are designed to represent genomic sequences. Identification of genomic sites that interact with a specific protein is based on competitive hybridization of the ChIP-enriched DNA and the ...
Kim, Tae Hoon, Dekker, Job
openaire   +3 more sources

ChIP

Cold Spring Harbor Protocols, 2018
ChIP is a powerful method for analyzing protein–DNA interactions that occur in vivo. A basic protocol involves immunoprecipitation of the cross-linked nucleoprotein complex and isolating and analyzing the DNA that is associated with the protein of interest.
Kim, Tae Hoon, Dekker, Job
openaire   +3 more sources

All Things ChIP: ChIP-Chip, ChIP-Seq, ChIP-PCR

2011
Chromatin immunoprecipitation (ChIP) has long been a valuable tool for scientists seeking to study in vivo protein–DNA interactions. Beginning with the pioneering efforts of Solomon et al., successful applications of the ChIP protocol have spanned multiple model systems across a wide breadth of biological disciplines.
Jason M. Rizzo, Michael J. Buck
openaire   +1 more source

Epigenetic Analysis: ChIP-chip and ChIP-seq

2011
The access of transcription factors and the replication machinery to DNA is regulated by the epigenetic state of chromatin. In eukaryotes, this complex layer of regulatory processes includes the direct methylation of DNA, as well as covalent modifications to histones. Using next-generation sequencers, it is now possible to obtain profiles of epigenetic
Pellegrini M, Ferrari R
openaire   +3 more sources

Chromatin Immunoprecipitation for ChIP-chip and ChIP-seq

2014
Bacterial adaptation to given environmental conditions is largely achieved by complex gene regulatory processes. To address the question how and to what extend single transcriptional regulators modulate gene expression, chromatin immunoprecipitation (ChIP) coupled to DNA microarrays (ChIP-chip) or to next-generation sequencing (ChIP-seq) is one of the ...
Sebastian Schulz, Susanne Häussler
openaire   +2 more sources

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