Results 191 to 200 of about 3,377,368 (288)

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N‐glycoprotein deglycosylation process in fungal homeostasis

The FEBS Journal, EarlyView.
In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras, Tanim Jabid Hossain, Magnus Karlsson, Georgios Tzelepis   +3 more
wiley   +1 more source

HcEcR Regulates Chitin Biosynthesis via 20E Signaling Rather Than Direct Transcriptional Activation in Hyphantria cunea Larvae. [PDF]

Arch Insect Biochem Physiol
Dong Z, Gao X, Li Y, Wu S, Wang Z, Zhang S, Zou C.   +6 more
europepmc   +1 more source

CP32, a novel anti‐oomycete cyclic peptide, interferes with cell‐wall deposition in Phytophthora infestans

Journal of Integrative Plant Biology, EarlyView.
The small cyclic peptide CP32 effectively inhibits Phytophthora infestans, the causal agent of potato and tomato late blight. Combined biochemical and phenotypic analyses demonstrate that CP32 disrupts cell wall biosynthesis, a key process in pathogen infection, resulting in a marked reduction of disease symptoms in plants.
Demetrio Marcianò, Stefano Rosa, Elena Marone Fassolo, Chiara Bertaso, Andrea Tagliani, Nina Gauri Capra, Federico Ballabio, Chiara Mizzotti, Giulia Rizzi, Sadia Fida Ullah, Lisa Kappel, Lucia Feni, Luca Tadini, Louise Jane Gourlay, Rosaria Russo, Vincent Bulone, Sabrina Pricl, Sandrine Ongeri, Sara Pellegrino, Carlo Camilloni, Silvia Laura Toffolatti, Vaibhav Srivastava, Paolo Pesaresi, Simona Masiero   +23 more
wiley   +1 more source

Three‐Dimensional Scaffolds for Bone, Soft Tissue, and Periodontal Regeneration

Journal of Periodontal Research, EarlyView.
Three‐dimensional scaffolds offer tissue‐specific control of architecture, mechanics, porosity, and functionalisation to improve bone, soft tissue, and periodontal regeneration. ABSTRACT The oral cavity presents three distinct regenerative challenges: restoration of alveolar bone volume and stability, augmentation of soft mucogingival tissues, and ...
Reuben Staples, Jamil Alayan, Raghavendra Vamsi Anegundi, Marisca Pereira, Saraswat Basu, Sašo Ivanovski   +5 more
wiley   +1 more source

Molecular origin of anisotropic shear elastoplasticity in chitin. [PDF]

Sci Adv
Wan Z, Lu Y, Yu Y, Niu X, Zhou C, Lu X, Yan Y, Smith JC, Srebnik S, Rojas OJ.   +9 more
europepmc   +1 more source

Successful use of insect‐based (Hermetia illucens) diet in dogs with food‐responsive enteropathy

Journal of Small Animal Practice, EarlyView.
Objective Diet is an integral component of the management of chronic enteropathy in dogs. The role of insect‐based diets in this disease remains unknown. The objective of this study was to evaluate the impact of an insect‐based (Hermetia illucens) diet in dogs with presumed food‐responsive enteropathy.
K. Murtagh, E. Stavroulaki, M. Carvalho, E. J. O'Neill, C. T. Mooney   +4 more
wiley   +1 more source

The structural language of fungal cell wall sugars in WHO priority fungi: the determinant of pathogenicity and the gateway to new therapies. [PDF]

Front Immunol
Trentin G, Martins-Santana L, Taborda CP, Almeida F.   +3 more
europepmc   +1 more source

Humanizing acidic mammalian chitinase variants establish lung immune conditioning and control environmentally driven inflammation and fibrosis. [PDF]

Cell Rep
Wang Y, Jung H, Kim DH, Liu E, Watza D, Risma SI, Florczak KL, Kim LM, Bou Reslan Z, Gupta A, Soni R, Díaz RE, Locksley RM, Fraser JS, Lee JS, Van Dyken SJ.   +15 more
europepmc   +1 more source

α‐1,3‐Glucan Is Required for Cell Wall Integrity and Full Virulence of Colletotrichum graminicola, but Not for Evasion of PAMP‐Triggered Immunity

Molecular Microbiology, EarlyView.
Abbreviated Summary The role of the major fungal cell wall polymer α‐1,3‐glucan in plant infection is poorly understood. Deletion mutants of the maize anthracnose fungus Colletotrichum graminicola lacking all three α‐1,3‐glucan synthase genes differentiated severely distorted biotrophic hyphae in planta, and virulence was strongly reduced.
Iris Gase, Lala Aliyeva‐Schnorr, Michael Melzer, Maria Ott, Julia Haufe, Matthias Menzel, Timo Engelsdorf, Christiane Rohrbach, Alan de Oliveira Silva, Lars M. Voll, Alexander S. Mickel, Maximilian Groß, Mamoru Wakayama, Holger B. Deising   +13 more
wiley   +1 more source

Biosynthesis, Physicochemical Characterization, and Functional Evaluation of Chitosan from <i>Ganoderma lucidum</i> for the Inhibition of Apple Brown Rot Caused by <i>Monilinia fructicola</i>. [PDF]

Molecules
Elshafie HS, Mohamed AA, Camele I.
europepmc   +1 more source