Results 111 to 120 of about 60,963 (257)

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Molecular dynamics simulations of oleuropein diffusion in chitosan‐based nanoparticles

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND This study explores the diffusion mechanisms of oleuropein (OLE), a promising polyphenolic compound, within chitosan‐based nanoparticles using molecular dynamics simulations. Chitosan nanoparticles serve as drug delivery carriers, leveraging biocompatibility and tunable release properties influenced by environmental factors such as ...
Bernardino Tirri, Andrea Lorenzoni, Francesco Mercuri, Pietro Calandra   +3 more
wiley   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Homologous Expression and Characterization of an LPMO from Commensal <i>Lactiplantibacillus plantarum</i> WCFS1 and Comparison with Related Enzymes from Chitin-Degrading Bacteria. [PDF]

ACS Omega
Berggreen H, Emrich-Mills TZ, Mathiesen G, Eijsink VGH, Forsberg Z.   +4 more
europepmc   +1 more source

Disclosing the production of fungal chitinases and proteases using insect by‐products as substrates in solid‐state fermentation

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The world population is projected to reach nearly 9.7 billion by 2050, significantly increasing the demand for novel and sustainable protein sources. Edible insects, such as Tenebrio molitor, emerge as promising alternatives due to their high nutritional value, but adult insects and frass are direct and abundant by‐products of this ...
Borja Fernández, Helena Fernandes, Nuno Muñoz‐Seijas, Francisco Soto‐Beltrán, José Manuel Domínguez, Helena Peres, José Manuel Salgado   +6 more
wiley   +1 more source

Low-affinity DNA-binding promotes cooperative activation of natural transformation in <i>Vibrio cholerae</i>. [PDF]

J Bacteriol
Hullinger AC, Callahan VE, Dalia TN, Dalia AB.   +3 more
europepmc   +1 more source

Water Table Decline Shifts Microbial Necromass From Particulate to Mineral‐Associated Pools in Peatlands

Land Degradation &Development, EarlyView.
ABSTRACT Microbial necromass carbon (MNC) is a major and stable component of soil organic carbon, yet its fraction‐specific accumulation and stabilization mechanisms remain unclear, particularly in peatlands experiencing hydrological change. We investigated MNC distribution along three independent transects spanning a natural gradient of five ...
Hua‐Bing Liu, Jun‐Qin Gao, Jia‐Tao Zhu, Xing‐Li Li, Xingliang Xu, Fei‐Hai Yu   +5 more
wiley   +1 more source

ZfpA-regulated chitin synthesis in <i>Aspergillus fumigatus</i> hyphae determines fungicidal tip lysis by FksA-targeting antifungals. [PDF]

Antimicrob Agents Chemother
Calise DG, Michaelis ML, Park SC, Wagner AS, Keller NP.   +4 more
europepmc   +1 more source

Higher NO3−‐N Levels Under Mulberry (Morus alba L.) Planting Enhanced CAZyme Abundance, Increasing Soil Carbon Stability

Land Degradation &Development, EarlyView.
ABSTRACT Afforestation is widely advocated for boosting carbon (C) sequestration. However, the stability of soil C pools in economically and culturally significant mulberry plantations remains poorly understood. The soil organic C (SOC) contents in different aggregates and the oxidizable OC fractions were measured.
Zi Yang, Weiguo Zhao, Jinjin Yang, Zhenjiang Wang, Weijun Zhu, Changyu Qiu, Qiang Lin, Meina Zhu, Mengdi Zhao   +8 more
wiley   +1 more source