Results 51 to 60 of about 42,176 (259)

Chitinase-Induced Airway Hyperreactivity and Inflammation in a Mouse Model of Nonallergic Asthma [PDF]

, 2021
Weber-Chrysochoou C, Darcan-Nicolaisen Y, Wohlgensinger J, et al. Chitinase-Induced Airway Hyperreactivity and Inflammation in a Mouse Model of Nonallergic Asthma. International archives of allergy and immunology.
Loeliger, Susanne, Wohlgensinger, Johanna, Hamelmann, Eckard, Darcan-Nicolaisen, Yasemin, Frei, Remo, Weber-Chrysochoou, Christina; https://orcid.org/, Lauener, Roger P, Weber-Chrysochoou, Christina, Tinner, Eva Maria, Yasemin Darcan-Nicolaisen, Susanne Loeliger, Remo Frei, Eckard Hamelmann, Johanna Wohlgensinger, Eva Maria Tinner, Roger P. Lauener, Christina Weber-Chrysochoou   +16 more
core   +2 more sources

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Advanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin, Jiani Li, Panqin Ma, Shinan Wu, Wenying Guan, Yimin Huang, Ke Feng, Mingyan Wei, Zixuan Yang, Shujia Guo, Caihong Huang, Yun‐Long Wu, Yi Han, Zuguo Liu   +13 more
wiley   +1 more source

Cloning and Expression of Class I Chitinase Genes from Four Mangrove Species under Heavy Metal Stress

Plants, 2023
Chitinases are believed to act as defense proteins when plants are exposed to heavy metal stress. Typical Class I chitinase genes were cloned from Bruguiera gymnorrhiza, Rhizophora stylosa, Kandelia obovata, and Avicennia marina using the methods of ...
Yue-Yue Zhou, You-Shao Wang, Cui-Ci Sun, Jiao Fei   +3 more
doaj   +1 more source

Targeting Mitochondrial Redox Signaling Promotes Neuroregeneration and Functional Recovery in a Multiple Sclerosis Model

Advanced Science, EarlyView.
Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima, Joshua Saylor, Shun Saito, Jinyan Zhou, Haruka Kawano, Shehata Anwar, Haruki Oba, Rachel Huezo, Miyu Okano, Haruki Matsuda, Makoto Kawatani, Kaori Honda, Hiroyuki Osada, Yuta Kikuchi, Masahito Ohue, Masami Ishibashi, Takayoshi Arai, Makoto Inoue, Midori A. Arai   +18 more
wiley   +1 more source

A Broad-Specificity Chitinase from Penicillium oxalicum k10 Exhibits Antifungal Activity and Biodegradation Properties of Chitin

Marine Drugs, 2021
Penicillium oxalicum k10 isolated from soil revealed the hydrolyzing ability of shrimp chitin and antifungal activity against Sclerotinia sclerotiorum. The k10 chitinase was produced from a powder chitin-containing medium and purified by ammonium sulfate
Xing-Huan Xie, Xin Fu, Xing-Yu Yan, Wen-Fang Peng, Li-Xin Kang   +4 more
doaj   +1 more source

Heterologous expression from Agrobacterium virulence promoters [PDF]

, 1991
The aim of this work was twofold: to construct plasmids with a gene encoding a pesticidal protein expressed from an Agrobacterium tumefaciens virulence promoter and to determine, in planta, the sites of Agrobacterium vir-induction.
Lilley, Catherine Jane, Lilley, C.J
core  

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source

Purification and Characterization of a Major Extracellular Chitinase from a Biocontrol Bacterium, Paenibacillus elgii HOA73

The Plant Pathology Journal, 2017
Chitinase-producing Paenibacillus elgii strain HOA73 has been used to control plant diseases. However, the antimicrobial activity of its extracellular chitinase has not been fully elucidated.
Yong Hwan Kim, Seur Kee Park, Jin Young Hur, Young Cheol Kim   +3 more
doaj   +1 more source

Isolation, screening and identification of haloarchaea with chitinolytic activity from hypersaline lakes of Iran [PDF]

Archives of Biological Sciences, 2019
Halophiles produce stable enzymes under extreme conditions. The scant information about chitinolytic haloarchaea led us to conduct the present study in order to isolate and screen native halophilic archaea with chitinolytic activity and to optimize the ...
Yavari-Bafghi Maryam, Babavalian Hamid, Amoozegar Mohammad Ali   +2 more
doaj   +1 more source

Functional analysis of the Arabidopsis thaliana AtEP3 endochitinase [PDF]

, 2001
Chitinases are enzymes that are capable of catalyzing the hydrolysis of chitin, a homopolymer of N-acetylglucosamine. Chitin is the main constituent of the exoskeleton of insects, of crustacean shells and of the cell wall of many fungi but is absent in ...
Passarinho, P.A.
core