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Preparation of Chito-Oligomers by Hydrolysis of Chitosan in the Presence of Zeolite as Adsorbent [PDF]

open access: yesMarine Drugs, 2016
An increasing interest has recently been shown to use chitin/chitosan oligomers (chito-oligomers) in medicine and food fields because they are not only water-soluble, nontoxic, and biocompatible materials, but they also exhibit numerous biological ...
Bassam El-Eswed   +2 more
exaly   +8 more sources

Computational Assessment of Chito-Oligosaccharides Interactions With Plasma Proteins [PDF]

open access: yesMarine Drugs, 2021
It is widely rec ognized that chitin and chitosan are potential sources of bioactive materials and that their oligosaccharides reveal various biological activities (including antimicrobial) that are correlated with their structures and physicochemical ...
Diana Larisa Roman   +2 more
exaly   +5 more sources

Virulence Vs. Immunomodulation: Roles of the Paracoccin Chitinase and Carbohydrate-Binding Sites in Paracoccidioides brasiliensis Infection [PDF]

open access: yesFrontiers in Molecular Biosciences, 2021
Paracoccin (PCN) is a bifunctional protein primarily present in the cell wall of Paracoccidioides brasiliensis, a human pathogenic dimorphic fungus. PCN has one chitinase region and four potential lectin sites and acts as both a fungal virulence factor ...
Nayla de Souza Pitangui   +3 more
doaj   +2 more sources

The use of lysozyme to prepare biologically active chitooligomers [PDF]

open access: yesPolímeros, 2015
Two types of crustacean commercial chitosans (CS1, CS2) were dissolved in lactic acid solutions, hydrolysed by lysozyme and finally fractioned by methanol solutions into two parts containing chito-oligomers (CS-O1, CS-O2).
Anna Zimoch-Korzycka   +4 more
doaj   +2 more sources

Computational Assessment of the Pharmacological Profiles of Degradation Products of Chitosan [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Chitosan is a natural polymer revealing an increased potential to be used in different biomedical applications, including drug delivery systems, and tissue engineering.
Diana Larisa Roman   +9 more
doaj   +2 more sources

Anti-inflammatory activity of soluble chito-oligosaccharides (CHOS) on VitD3-induced human THP-1 monocytes.

open access: yesPLoS ONE, 2021
Chito-oligosaccharides (CHOS) are oligomers of D-glucosamine and N-acetyl-glucosamine. Anti-inflammatory activities of a wide variety of CHOS mixtures have previously been reported, mainly based on studies with mouse models and murine macrophages.
Paiboon Jitprasertwong   +7 more
doaj   +2 more sources

ANTIBACTERIAL ACTIVITY OF CHITOSAN AND ITS OLIGOMERS ON SOME PATHOGENIC BACTERIA ISOLATED FROM SOME MILK PRODUCTS [PDF]

open access: yesAssiut Veterinary Medical Journal, 1999
Chitosan and its oligomers N-acetyl chitooligosaccharides and chito-oligosaccharides prepared by deacetylation and chemical hydrolysis, respectively and have a broad antimicrobial spectrum to Gram-positive (Staph.aureus and List.
ELSHERIF WALAA, MANAL AMIN
doaj   +1 more source

Endo-chitinase Chit33 specificity on different chitinolytic materials allows the production of unexplored chitooligosaccharides with antioxidant activity

open access: yesBiotechnology Reports, 2020
The biological activity of chitooligosaccharides (COS) has made them targets for industrial and medical sectors. In this work, endo-chitinase Chit33 from Trichoderma harzianum CECT 2413 was expressed in Pichia pastoris GS115 to levels never achieved ...
Peter Elias Kidibule   +3 more
doaj   +1 more source

Synthesis of Biotin-Tagged Chitosan Oligosaccharides and Assessment of Their Immunomodulatory Activity

open access: yesFrontiers in Chemistry, 2020
Chitin, a polymer of β-(1→4)-linked N-acetyl-d-glucosamine, is one of the main polysaccharide components of the fungal cell wall. Its N-deacetylated form, chitosan, is enzymatically produced in the cell wall by chitin deacetylases.
Yury E. Tsvetkov   +4 more
doaj   +1 more source

Use of chitin and chitosan to produce new chitooligosaccharides by chitinase Chit42: enzymatic activity and structural basis of protein specificity

open access: yesMicrobial Cell Factories, 2018
Background Chitinases are ubiquitous enzymes that have gained a recent biotechnological attention due to their ability to transform biological waste from chitin into valued chito-oligomers with wide agricultural, industrial or medical applications.
Peter Elias Kidibule   +8 more
doaj   +1 more source

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