Results 171 to 180 of about 4,781 (194)
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1988
Publisher Summary This chapter describes a rapid and sensitive procedure for simultaneous determination of chitooligosaccharides and reduced chitooligosaccharides by HPLC and its application for studies on the mode of action of chitinase and β-N-acetylhexosaminidase.
Akira Ohtakara, Masaru Mitsutomi
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Publisher Summary This chapter describes a rapid and sensitive procedure for simultaneous determination of chitooligosaccharides and reduced chitooligosaccharides by HPLC and its application for studies on the mode of action of chitinase and β-N-acetylhexosaminidase.
Akira Ohtakara, Masaru Mitsutomi
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Sulfated chitooligosaccharides as prolyl endopeptidase inhibitor
International Journal of Biological Macromolecules, 2007Prolyl endopeptidase (PEP, EC 3.4.21.26) is a proline-specific endopeptidase with a serine-type mechanism, which digests small peptide-like hormones, neuroactive peptides, and various cellular factors. PEP has been involved in neurodegenerative disorders, therefore, the discovery of PEP inhibitors can revert memory loss caused by amnesic compounds.
Jae-Young, Je +7 more
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Chitooligosaccharides: Synthesis, characterization and applications
Polymer Science Series A, 2011Chitosans with high degree of polymerization and molecular weight exhibit poor aqueous solubility which is an impediment in their applicability. The low molecular weight chitosans (LMWCs) and chitooligosaccharides (COSs) can be used to avoid this hurdle.
V. K. Mourya +2 more
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Concise preparation of biologically active chitooligosaccharides
Natural Product Research, 2009Chitooligosaccharides (COSs) have demonstrated a diverse array of biological activities. Here we report a concise preparation method for tetra-N-acetyl-chitotetraose and penta-N-acetyl-chitopentaose. The FACE analysis showed that the partially N-acetylated COS mixture mainly contained glucosamine (GlcN) and some oligomers [(GlcN)(n), n = 2-7].
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Anti-angiogenic activities of chitooligosaccharides
Carbohydrate Polymers, 2008Abstract Chitooligosaccharides (COS) was obtained from chitosan by depolymerization with enzyme and analyzed by HPLC and TOF-MS, and the results indicated that the polymerization degree of COS was 2–18. In order to explore the anti-angiogenic activities of COS, the effect of COS on chicken chorioallantoic membrane (CAM) angiogenesis and on ...
Haige Wu +4 more
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Liquid crystalline behaviour of chitooligosaccharides
Carbohydrate Polymers, 2004Abstract Two chitooligosaccharide samples (COS1 and COS2) were prepared by enzymatic degradation of chitosan. The molecular weight of the main component was determined by mass spectrometry to be 2340 and 4303, respectively. They showed cholesteric liquid crystal structures in concentrated solutions.
Dong, YM +6 more
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Enzymatic preparation of chitooligosaccharides by commercial lipase
Food Chemistry, 2008The effect of a commercial lipase on chitosan degradation was investigated. When four chitosans with various degrees of deacetylation were used as substrates, the lipase showed higher optimal pH toward chitosan with higher DD (degree of deacetylation). The optimal temperature of the lipase was 55°C for all chitosans.
Dong-Xia, Lee +2 more
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New access to lipo-chitooligosaccharide nodulation factors
Organic & Biomolecular Chemistry, 2004Sulfonated and non-sulfonated lipo-chitooligosaccharides involved in Sinorhizobium meliloti-legume symbiosis are efficiently obtained on a multi mg scale by a 2-step procedure combining biotechnological and chemical approaches.
Rasmussen, M. O. +4 more
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Nanodots functionalized with chitooligosaccharides for blocking chitoporins
Colloids and Surfaces B: BiointerfacesWe report the synthesis of functionalized nanodots as potential powerful blockers of solute transport through a chitoporin. Ultrasmall silica nanocapsules with a diameter of ∼ 6 nm were coated with chitooligosaccharides to be used as a "lid" binding to the opening of the chitoporin VhChiP of Vibrio campbellii.
Thao P. Doan-Nguyen +6 more
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