Results 201 to 210 of about 32,119 (253)
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Pectinase‐Based Bioprocesses for Circular Bioeconomy and Sustainable Industrial Development
Biotechnology and Bioengineering, EarlyView.This picture demonstrates a unified strategy for sustainable pectinase production, focusing on microbial bioproduction, innovative strategies in enzyme engineering (Protein engineering, rational enzyme design, directed evolution and heterologous expression) and various applications in industry, including food, textiles, pulp and paper, agriculture and ...
Nisha Sharma +6 more
wiley +1 more source
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Biomedical Application of Chitosan and Chitosan Derivatives: A Comprehensive Review
Current Pharmaceutical Design, 2023Abstract: Chitosan (CS) is a widely known naturally occurring polysaccharide made of chitin. The Low solubility of chitosan in water restricts its use in medical applications. However, several chemical modifications have made chitosan superior in solubility, biocompatibility, biodegradability, stability, and easy functionalization ability.
Bappaditya Chatterjee
exaly +3 more sources
Antimicrobial Properties of Chitosan and Chitosan Derivatives
2016The investigations of chitosan as an antimicrobial substance came into focus in the 1990s. The number of publications on this topic has been rapidly increasing since then, with more than 2,500 papers published in 2020. Initially, the interest was mainly related to potential applications in agriculture and food products, but currently, the emphasis on ...
Priyanka Sahariah +2 more
openaire +2 more sources
Application of chitosan and chitosan derivatives as biomaterials
Journal of Industrial and Engineering Chemistry, 2016Abstract Chitosan is a linear polysaccharide composed of randomly distributed β-(1-4)-linked d -glucosamine and N-acetyl- d -glucosamine. It is one of the major cationic polymers and the second most abundant polysaccharides in nature. It is extensively used to the biomedical and the industrial fields. Specially, chitosan has been studied much in the
Changyong Choi +2 more
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International Journal of Biological Macromolecules, 2009
Chitosan, carboxymethyl chitosan (CMCS) and chitosan sulfates (CSS) with different molecular weight were modified by reacting with 4-hydroxyl-5-chloride-1,3-benzene-disulfo-chloride or 2-hydroxyl-5-chloride-1,3-benzene-disulfo-chloride to give 12 kinds of new hydroxylbenzenesulfonailides derivatives of them.
Zhimei, Zhong +3 more
openaire +2 more sources
Chitosan, carboxymethyl chitosan (CMCS) and chitosan sulfates (CSS) with different molecular weight were modified by reacting with 4-hydroxyl-5-chloride-1,3-benzene-disulfo-chloride or 2-hydroxyl-5-chloride-1,3-benzene-disulfo-chloride to give 12 kinds of new hydroxylbenzenesulfonailides derivatives of them.
Zhimei, Zhong +3 more
openaire +2 more sources
Chitosan and Derivatives: Bioactivities and Application in Foods
Annual Review of Food Science and Technology, 2021Chitosan is a biodegradable, biocompatible, and nontoxic aminopolysaccharide. This review summarizes and discusses the structural modifications, including substitution, grafting copolymerization, cross-linking, and hydrolysis, utilized to improve the physicochemical properties and enhance the bioactivity and functionality of chitosan and related ...
Da-Yong, Zhou +6 more
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Chitosan and Chitosan Derivatives in Drug Delivery and Tissue Engineering
2011Chitosan is a nontoxic, biodegradable, and biocompatible polysaccharide of β(1-4)-linked d-glucosamine and N-acetyl-d-glucosamine. This derivative of natural chitin presents remarkable properties that have paved the way for the introduction of chitosan in the biomedical and pharmaceutical fields.
Riva, Raphaël +5 more
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Chitin and Chitosan Derivatives
2013Part I Synthesis and Characterization of Chitin and Chitosan Derivatives Chitin and Chitosan Derivatives Se-Kwon Kim and Jayachandran Venkatesan Synthesis, Characterization, and Biomedical Applications of Chitosan and Its Derivatives Hans E. Junginer and Assal M. M.
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Bioorganic & Medicinal Chemistry, 2007
Chitosan (CS) and chitosan sulfates (CSS) with different molecular weight (Mw) were reacted with 4-acetamidobenzene sulfonyl chloride to obtain sulfanilamide derivatives of chitosan and chitosan sulfates (LSACS, HSACS, LSACSS, HSACSS). The preparation conditions such as different reaction time, temperature, solvent, and the molar ratio of reaction ...
Zhimei, Zhong +6 more
openaire +2 more sources
Chitosan (CS) and chitosan sulfates (CSS) with different molecular weight (Mw) were reacted with 4-acetamidobenzene sulfonyl chloride to obtain sulfanilamide derivatives of chitosan and chitosan sulfates (LSACS, HSACS, LSACSS, HSACSS). The preparation conditions such as different reaction time, temperature, solvent, and the molar ratio of reaction ...
Zhimei, Zhong +6 more
openaire +2 more sources