Results 81 to 90 of about 164,858 (250)

Developing and testing accelerated partner therapy for partner notification for people with genital Chlamydia trachomatis diagnosed in primary care: a pilot randomised controlled trial [PDF]

, 2015
Background Accelerated partner therapy (APT) is a promising partner notification (PN) intervention in specialist sexual health clinic attenders. To address its applicability in primary care, we undertook a pilot randomised controlled trial (RCT) of two
Althaus, Andrew Copas, Anne M Johnson, Bailey, Cassell, Catherine H Mercer, Centers for Disease Control and Prevention, Chen, Claudia S Estcourt, Cowan, Estcourt, Estcourt, Ferreira, Greta Rait, Götz, Jackie A Cassell, Kazeem Aderogba, Laura Tickle, Lorna J Sutcliffe, Louise J Jackson, Low, Low, McCarney, McNulty, McNulty, McNulty, Mercer, Mercer, Mercer, Merle Symonds, Miller, Pamela Muniina, Roberts, Sarah Creighton, Shackleton, Tracy E Roberts, Turner   +36 more
core   +6 more sources

Relationships Between European Wildcats and Domestic Cats in an Area of Sympatry: Exploring Key Conservation Questions on Hybridization and Disease Transmission

Animal Conservation, EarlyView.
We have found evidence of behavioural barriers for both hybridization and disease transmission between European wildcats and domestic cats. This includes hierarchical interspecies exclusion enforced by wildcats, as well as sexual selection exerted by wildcat females.
Jose María Gil‐Sánchez, Elena Bertos, Mariola Sánchez‐Cerdá, Emilio Virgós, Marcos Moleón   +4 more
wiley   +1 more source

Community-Acquired Pneumonia Caused by Avian Chlamydia abortus, the Netherlands

Emerging Infectious Diseases
We report avian Chlamydia abortus pneumonia in an immunocompetent elderly patient in the Netherlands after environmental exposure to wild aquatic birds, including seabirds. New molecular surveillance studies are needed in wild and captive birds, as well
Jairo Gooskens, Einar H.R. van Essen, Margriet E.M. Kraakman, Patrick Wörz, Edou R. Heddema, Stefan A. Boers   +5 more
doaj   +1 more source

Genital Infiltrations of CD4+ and CD8+ T Lymphocytes, IgA+ and IgG+ Plasma Cells and Intra-Mucosal Lymphoid Follicles Associate With Protection Against Genital Chlamydiatrachomatis Infection in Minipigs Intramuscularly Immunized With UV-Inactivated Bacteria Adjuvanted With CAF01

Frontiers in Microbiology, 2019
The development of a vaccine against genital chlamydia in women is advancing, and the evaluation of in situ immune responses following vaccination and challenge infections is crucial for development of a safe and protective vaccine.
Karin Erneholm, Karin Erneholm, Emma Lorenzen, Emma Lorenzen, Sarah Bøje, Sarah Bøje, Anja Weinreich Olsen, Gregers Jungersen, Henrik E. Jensen, Joseph P. Cassidy, Peter Andersen, Jørgen S. Agerholm, Frank Follmann   +12 more
doaj   +1 more source

Can remote STI/HIV testing and eClinical Care be compatible with robust public health surveillance? [PDF]

, 2015
In this paper we outline the current data capture systems for human immunodeficiency virus (HIV) and sexually transmitted infection (STI) surveillance used by Public Health England (PHE), and how these will be affected by the introduction of novel ...
Estcourt, C, Gibbs, J, Gill, N, Harding-Esch, EM, Hughes, G, Lowndes, C, Mohammed, H, Nardone, A, Sadiq, ST, Sonnenberg, P, Sutcliffe, L   +10 more
core   +2 more sources

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

The Seroprevalence of Chlamydia abortus in Montana Domestic Rangeland Sheep Varies by Breed, Flock and Herding Practices. [PDF]

Vet Med Sci
Ovine enzootic abortion, caused by Chlamydia abortus, leads to significant reproductive losses in sheep. This study found 12.6% of 781 sheep in Montana tested positive for antibodies with differences by breed, flock and herding status. ABSTRACT Background Ovine enzootic abortion (OEA) is a reproductive disease in domestic sheep characterized by late ...
Simmons AJ, Borgogna JC, Roeder BL, Yeoman CJ, Posbergh CJ.   +4 more
europepmc   +2 more sources

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

A time series model of CDS sequences in complete genome [PDF]

, 2000
A time series model of CDS sequences in complete genome is proposed. A map of DNA sequence to integer sequence is given. The correlation dimensions and Hurst exponents of CDS sequences in complete genome of bacteria are calculated. Using the average of
Wang, Bin, Yu, Zu-Guo
core   +2 more sources