Recent advances in understanding and managing Chlamydia trachomatis infections
Worldwide, Chlamydia trachomatis infections rank among the most common sexually transmitted infections (STI), and cause notable reproductive morbidity in women.
J. Marrazzo, R. Suchland
semanticscholar +1 more source
Chlamydia control activities in Europe: cross-sectional survey [PDF]
Background: Chlamydia is the most commonly reported bacterial sexually transmitted infection in Europe. The objective of the Screening for Chlamydia in Europe (SCREen) project was to describe current and planned chlamydia control activities in Europe.
A. Martin Hilber+23 more
core +1 more source
ABSTRACT Background Sexually transmitted infections (STIs), caused by Neisseria gonorrhoeae, Treponema pallidum and Chlamydia trachomatis, are increasing across Europe, which prompts dermatologists to be more involved in their detection and management.
Andrei Tanasov+6 more
wiley +1 more source
Efficacy of Apremilast in Refractory Genital Psoriasis: A Retrospective Case Series
ABSTRACT Background Genital pustular psoriasis is a rare and often underdiagnosed condition that can severely affect physical comfort, quality of life and psychological well‐being. It can be particularly challenging to manage, often requiring systemic therapies due to its potential unresponsiveness to conventional topical treatment.
Jonathan Krygier+2 more
wiley +1 more source
TESTING PATTERNS FOR SYPHILIS AND OTHER SEXUALLY TRANSMITTED INFECTIONS IN PREGNANT WOMEN PRESENTING TO EMERGENCY DEPARTMENTS [PDF]
Following an initial decrease in the incidence of congenital syphilis from 2008-2012, the rate of congenital syphilis rose by 38% across the United States between 2012-2014 (2).
SHOYOMBO, IFEOLUWA
core +1 more source
Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis [PDF]
Background—Studies have suggested that the prevalence of antibodies against heat-shock proteins (HSPs), Chlamydia pneumoniae (Cpn), and cytomegalovirus (CMV) is associated with coronary artery disease (CAD), but the independent or joint effects of ...
Berencsi, Klára+11 more
core +1 more source
Mapping protein–protein interactions by mass spectrometry
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu+4 more
wiley +1 more source
National Institute of Allergy and Infectious Diseases workshop report: "Chlamydia vaccines: The way forward". [PDF]
Chlamydia trachomatis (Ct), an intracellular pathogen, is the most common bacterial sexually transmitted infection. In addition to acute cervicitis and urethritis, Ct can lead to serious sequelae of significant public health burden including pelvic ...
Brunham, Robert C+4 more
core +1 more source
Protection of outbred mice against a vaginal challenge by a Chlamydia trachomatis serovar E recombinant major outer membrane protein vaccine is dependent on phosphate substitution in the adjuvant. [PDF]
Chlamydia trachomatis is the most common bacterial sexually-transmitted pathogen for which there is no vaccine. We previously demonstrated that the degree of phosphate substitution in an aluminum hydroxide adjuvant in a TLR-4-based C. trachomatis serovar
Ausar, Salvador Fernando+7 more
core +1 more source
Immunology of Chlamydia infection: implications for a Chlamydia trachomatis vaccine [PDF]
Sexually transmitted Chlamydia trachomatis infections are a serious public-health problem. With more than 90 million new cases occurring annually, C. trachomatis is the most common cause of bacterial sexually transmitted disease worldwide. Recent progress in elucidating the immunobiology of Chlamydia muridarum infection of mice has helped to guide the ...
Robert C. Brunham, Jose Rey-Ladino
openaire +3 more sources