Can we evaluate population screening strategies in UK general practice? A pilot randomised controlled trial comparing postal and opportunistic screening for genital chlamydial infection [PDF]
STUDY OBJECTIVE: To assess whether opportunistic and postal screening strategies for Chlamydia trachomatis can be compared with usual care in a randomised trial in general practice DESIGN: Feasibility study for a randomised controlled trial. SETTING:
Craig, N.+7 more
core +2 more sources
Recent advances in understanding and managing Chlamydia trachomatis infections
Worldwide, Chlamydia trachomatis infections rank among the most common sexually transmitted infections (STI), and cause notable reproductive morbidity in women.
J. Marrazzo, R. Suchland
semanticscholar +1 more source
FIGO position statement: Gamete donations
Abstract Gamete donation has become a crucial part of Assisted Reproductive Technologies (ARTs), providing hope to individuals, including those who may have no other option for parenthood. This process comes with a wide range of ethical, medical, and legal challenges that need to be carefully addressed to protect the well‐being and rights of all ...
Laurie Henry+20 more
wiley +1 more source
Chlamydia Persistence: A Survival Strategy to Evade Antimicrobial Effects in-vitro and in-vivo
The Chlamydiaceae comprise a group of highly adapted bacterial pathogens sharing a unique intracellular lifestyle. Three Chlamydia species are pathogenic to humans: Chlamydia trachomatis, Chlamydia pneumoniae, and Chlamydia psittaci. C.
Maria Emilia Panzetta+2 more
doaj +1 more source
A sharp threshold for a modified bootstrap percolation with recovery [PDF]
Bootstrap percolation is a type of cellular automaton on graphs, introduced as a simple model of the dynamics of ferromagnetism. Vertices in a graph can be in one of two states: `healthy' or `infected' and from an initial configuration of states, healthy vertices become infected by local rules.
arxiv +1 more source
Improved effectiveness of partner notification for patients with sexually transmitted infections: systematic review [PDF]
Objective: To examine the effectiveness of methods to improve partner notification by patient referral (index patient has responsibility for informing sex partners of their exposure to a sexually transmitted infection).
Cassell, Jackie A+4 more
core +2 more sources
Rare Infectious Diseases: Detection and Clinical Implications
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian+7 more
wiley +1 more source
PDE model for multi-patch epidemic models with migration and infection-age dependent infectivity [PDF]
We study a stochastic epidemic model with multiple patches (locations), where individuals in each patch are categorized into three compartments, Susceptible, Infected and Recovered/Removed, and may migrate from one patch to another in any of the compartments.
arxiv
The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling [PDF]
Chlamydia trachomatis, the causative agent of trachoma and sexually transmitted infections, employs a type III secretion (T3S) system to deliver effector proteins into host epithelial cells to establish a replicative vacuole.
Bastidas, Robert J.+6 more
core +3 more sources
Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence
ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab+4 more
wiley +1 more source