Adolescent girls and young women represent a key risk group for sexually transmitted infections (STIs). The vaginal microbiota is thought to play an important role in susceptibility to STIs such as Chlamydia trachomatis. We compared the microbiota of the
Christina Balle+12 more
semanticscholar +1 more source
Comparison of four serological assays for the diagnosis of Chlamydia trachomatis in subfertile women [PDF]
Introduction: Chlamydia antibody testing (CAT) in serum has been introduced as a screening method in the infertility workup. We evaluated the test characteristics of two ELISA tests compared to micro-immunofluorescence tests (MIFs).
Claeys, Geert+7 more
core +1 more source
Nonoptimal Vaginal Microbiota After Azithromycin Treatment for Chlamydia trachomatis Infection
We characterized the composition and structure of the vaginal microbiota in a cohort of 149 women with genital Chlamydia trachomatis infection at baseline who were followed quarterly for 9 months after antibiotic treatment.
Jeanne Tamarelle+11 more
semanticscholar +1 more source
National Institute of Allergy and Infectious Diseases workshop report: "Chlamydia vaccines: The way forward". [PDF]
Chlamydia trachomatis (Ct), an intracellular pathogen, is the most common bacterial sexually transmitted infection. In addition to acute cervicitis and urethritis, Ct can lead to serious sequelae of significant public health burden including pelvic ...
Brunham, Robert C+4 more
core +1 more source
Chlamydia trachomatis Infection of the Neovagina in Transgender Women
We report 2 cases of neovaginal Chlamydia trachomatis infection in transgender women who underwent penile-inversion vaginoplasty procedures with integrated peritoneum and urethral grafts. These tissue types may have facilitated C.
A. Radix+4 more
semanticscholar +1 more source
Current Status of Trachoma Infections and a Discussion on Treatment Approaches: A Comparative Analysis of Azithromycin and Doxycycline [PDF]
Chlamydia trachomatis causes a wide range of diseases, affecting the eyes, genital tract, and other organs, and can also lead to mother-to-child transmission.
Lin Runkun
doaj +1 more source
Using an agent-based sexual-network model to analyze the impact of mitigation efforts for controlling chlamydia [PDF]
Chlamydia trachomatis (Ct) is the most reported sexually transmitted infection in the United States with a major cause of infertility and pelvic inflammatory disease among women. Despite decades of screening women for Ct, rates increase among young African Americans (AA). We create and analyze an agent-based network model to understand the spread of Ct.
arxiv +1 more source
Protection of outbred mice against a vaginal challenge by a Chlamydia trachomatis serovar E recombinant major outer membrane protein vaccine is dependent on phosphate substitution in the adjuvant. [PDF]
Chlamydia trachomatis is the most common bacterial sexually-transmitted pathogen for which there is no vaccine. We previously demonstrated that the degree of phosphate substitution in an aluminum hydroxide adjuvant in a TLR-4-based C. trachomatis serovar
Ausar, Salvador Fernando+7 more
core +1 more source
Chlamydia trachomatis is the most common cause of sexually transmitted infection. In 75% of women and 50% of men infection is asymptomatic. According to World Health Organization reports, the number of new genital infections with Chlamydia trachomatis ...
Parvin Hassanzadeh+5 more
doaj +1 more source
Chlamydial infection from outside to inside [PDF]
Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic developmental cycle. Specific interactions with the host cell are crucial for the bacteria's survival and amplification because of the reduced chlamydial genome.
Gitsels, Arlieke+2 more
core +2 more sources