Results 91 to 100 of about 5,109 (221)

A Chlamydia effector recruits CEP170 to reprogram host microtubule organization [PDF]

, 2015
The obligate intracellular bacterial pathogen Chlamydia trachomatis deploys virulence effectors to subvert host cell functions enabling its replication within a specialized membrane-bound compartment termed an inclusion.
Abdelrahman, Al-Younes, Al-Zeer, Alzhanov, Archuleta, Bannantine, Beatty, Carabeo, Cocchiaro, D'Avino, Delevoye, Dumoux, Eliceiri, Gauliard, Grieshaber, Guarguaglini, Hoare, Hybiske, Jewett, Johnson, Koskela, Kumar, Lane, Leonhardt, Lutter, Maliga, Miroux, Mital, Mital, Nans, Nigg, Peters, Radhakrishman, Richards, Romano, Rzomp, Schmid, Schwan, Scidmore, Smith, Welburn, Wilson, Woodruff   +42 more
core   +3 more sources

Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis

Immunology, EarlyView.
Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay, Mariem Garci, Ahmed Baligh Laaribi, Nabil Mathlouthi, Imene Ouzari   +4 more
wiley   +1 more source

Transcriptional Landscape of Waddlia chondrophila Aberrant Bodies Induced by Iron Starvation

Microorganisms, 2020
Chronic infections caused by obligate intracellular bacteria belonging to the Chlamydiales order are related to the formation of persistent developmental forms called aberrant bodies (ABs), which undergo DNA replication without cell division.
Silvia Ardissone, Aurélie Scherler, Trestan Pillonel, Virginie Martin, Carole Kebbi-Beghdadi, Gilbert Greub   +5 more
doaj   +1 more source

Transcriptional analysis of persistent Chlamydia pneumoniae infection in vitro [PDF]

, 2011
Chlamydia pneumoniae can cause acute respiratory infections including pneumonia. Repeated and persistent Chlamydia infections occur and persistent C. pneumoniae infection may have a role in the pathogenesis of atherosclerosis and coronary heart disease ...
Mannonen, Laura
core  

Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]

, 2017
Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo, Lepanto, Maria Stefania, Paesano, Rosalba, Rosa, Luigi, Valenti, Piera   +4 more
core   +2 more sources

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Diagnostic Value of PCR and ELISA for Chlamydia trachomatis in a Group of Asymptomatic and Symptomatic Women in Isfahan, Iran [PDF]

International Journal of Fertility and Sterility, 2009
Background Chlamydia trachomatis infections are the most prevalent sexually transmitted bacterial infections (STI) in the world that lead to a cause of tubal factor infertility in women. The aim of this study is to determine the presence of C.trachomatis
Anahita Jenab, Naser Golbang, Pouran Golbang, Leili Chamani-Tabriz, Rasoul Roghanian   +4 more
doaj   +1 more source

Bacterial Toxin Exploits Host Membrane Phospholipid as a Receptor for Binding, Entry, and Cytopathogenicity

Molecular Microbiology, EarlyView.
Mycoplasma pneumoniae pathogenesis relies on its CARDS toxin, which initiates cell binding and subsequent uptake by exploiting sphingomyelin, a key phospholipid found in the host plasma membrane. Maximal cellular entry and full cytotoxic effects are achieved through a synergistic mechanism that involves interaction with the protein coreceptor annexin ...
Alejandra M. Kirkpatrick, Thirumalai R. Kannan   +1 more
wiley   +1 more source

A novel inhibitor of Chlamydophila pneumoniae protein kinase D (PknD) inhibits phosphorylation of CdsD and suppresses bacterial replication

BMC Microbiology, 2009
Background We have shown previously that Chlamydophila pneumoniae contains a dual-specific Ser/Thr protein kinase that phosphorylates CdsD, a structural component of the type III secretion apparatus.
Bulir David C, Stone Chris B, Johnson Dustin L, Coombes Brian K, Mahony James B   +4 more
doaj   +1 more source

Cell wall precursors are required to organize the chlamydial division septum. [PDF]

, 2014
Members of the Chlamydiales order are major bacterial pathogens that divide at mid-cell, without a sequence homologue of the FtsZ cytokinetic tubulin and without a classical peptidoglycan cell wall.
Frandi, A., Greub, G., Jacquier, N., Pillonel, T., Viollier, P., Viollier, P.H.   +5 more
core   +2 more sources