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The purpose of this chapter is to define what one do and do not know about chlamydial persistence with the goal of determining the extent of the role that persistence plays in chlamydial disease (if at all) and what one should do to better understand this chlamydial attribute. Out of P. falciparum, P. vivax, P. malariae, and P.
Gerald I. Byrne, Wandy L. Beatty
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Persistence, Relapses, and Reinfections of Chlamydial Infections
Chlamydial infections can remain clinically silent for a considerable period of time. Both human beings and animals can be carriers of C. trachomatis and C. psittaci for years.
Pers-Anders Mårdh +2 more
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Persistent Urethral Leukocytosis and Asymptomatic Chlamydial Urethritis
Journal of Infectious Diseases, 1979Chlamydia trachomatis was isolated from 47% of asymptomatic, sexually active men whose urethral smears contained four or more polymorphonuclear leukocytes (PMN) per high-power field (hpf) one week after their sexual activity was restricted. C. trachomatis was not detected in any of 23 asymptomatic, sexually active men having less than 4 PMN/hpf in two ...
S L, Swartz, S J, Kraus
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Role of Tryptophan in Gamma Interferon‐Mediated Chlamydial Persistence
Wandy L. Beatty +4 more
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Diseases caused by C. trachomatis have an adverse impact on male and female health and the reproductive function and are among the leading causes of infertility. Even though C. trachomatis is a sexually transmitted pathogen adapted to the epithelial cells of the urogenital tract (UGT), it has a fairly wide tropism and can infect blood cells ...
N. E. Bondareva +2 more
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Persistence of Chlamydial genital infection -how common is it ?
Jyoti Dhar
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Implications for persistent chlamydial infections of phagocyte-microorganism interplay
European Journal of Clinical Microbiology & Infectious Diseases, 1991In vitro models of Chlamydia trachomatis inhibition by cytokines, human-monocyte derived macrophages (HMDM) and human polymorphonuclear leukocytes (HPMN) are discussed in an attempt to delineate the molecular basis of parasite-host cell interplay in persistent and chronic chlamydial infection. Interferon gamma (IFN) has been found to reversibly inhibit
I, Sarov +7 more
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Electron microscopic evidence of persistent chlamydial infection following treatment
Journal of the European Academy of Dermatology and Venereology, 2001Abstract Chlamydia trachomatis infections of the female and male genital tracts are often asymptomatic and, thus, tend to become persistent. In the persistent state the typical Chlamydia life cycle is arrested and standard antibiotic regimens do not always eradicate this infection. We sought to relate treatment failures in men and women with persistent
E Y, Bragina +2 more
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Augmented oxidative stress in infertile women with persistent chlamydial infection
Reproductive Biology, 2017There is established association between oxidative stress, infections of genital tract and fertility. Genital tract infections may provoke increased production of free radicals and generate oxidative stress that can be involved in pathophysiology of a number of reproductive diseases and complications during pregnancy.
Jelena, Tošić-Pajić +8 more
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