Herpes simplex virus co-infection-induced Chlamydia trachomatis persistence is not mediated by any known persistence inducer or anti-chlamydial pathway [PDF]
Several inducers of chlamydial persistence have been described, including interferon-gamma (IFN-gamma), IFN-alpha, IFN-beta, and tumour necrosis factor-alpha (TNF-alpha) exposure, and iron, amino acid or glucose deprivation. A tissue-culture model of Chlamydia trachomatis/herpes simplex virus type-2 (HSV-2) co-infection indicates that viral co ...
Jennifer Vanover +5 more
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Persistent Superficial Punctate Keratitis After Resolution of Chlamydial Follicular Conjunctivitis
Cornea, 1992Two cases of follicular conjunctivitis due to Chlamydia trachomatis followed by punctate epithelial keratitis are described. Both cases were initially treated with either oral tetracycline or doxycycline with resolution of the follicles. These two patients subsequently had recurrent, bilateral grayish lesions at various levels in the corneal epithelium
D R, Hardten +3 more
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Presentation of clinically suspected persistent chlamydial infection: a case series
International Journal of STD & AIDS, 2013In vivo antimicrobial resistance has yet to be documented in Chlamydia trachomatis; however, there have been anecdotal reports of persistent infection. The purpose of this case series was to describe a group of patients who have persistent chlamydia infection despite adequate treatment and where re-infection was considered unlikely.
Pitt, R. A. +3 more
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The persistence of chlamydial inclusions in clinically quiescent trachoma.
Most of the trachoma patients seen at the Guinness Eye Clinic in Kaduna, Northern Nigeria today are in the healed or quiescent stages of evolution and disease intensity is largely trivial. A significant proportion however, seem to have recrudescence of the active stages, a phenomenon that is usually attributed to reinfection.
Babalola Oe, Bage Sd
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[Inapparent persistent chlamydial infection in McCoy cells].
Revue canadienne de biologie, 1981We have studied the phenomena of inapparent chlamydial infections in vitro using McCoy cells in culture as hosts and low doses of Chlamydia psittaci (GP-IC) as infecting agents. The results indicate that GP-IC can persist undetected at least 220 hrs in McCoy cells previously inoculated with 0.2 mL of a GP-IC preparation containing 30 ifu/mL, using the ...
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Chlamydia trachomatis Growth Inhibition by IFNγ: Implications for Persistent Chlamydial Infections
2021The immune response to chlamydial infections and the role it plays in resistance to reinfection, resolution of ongoing infection, and development of persistent chlamydial infection is poorly understood. Inhibition of chlamydial growth as a result of deprivation of necessary metabolites, such as certain amino acids, has been described previously and ...
Yonat Shemer, Israel Sarov
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Cell-mediated immune responses to chlamydial and common recall antigens were measured in 26 subjects whose clinical signs of trachoma persisted over 6 months of follow-up and in 21 subjects whose clinical signs resolved spontaneously over the same period.
R L, Bailey +3 more
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A case of renal involvement in persistent immune activation caused by chlamydial salpingitis
Virchows Archiv, 2001A 24-year-old woman presented with renal insufficiency, macrohematuria, and mild urinary protein. Polyclonal hypergamma-globulinemia, thrombocytosis, increased concentration of serum, and urinary interleukin (IL)-6 all indicated persistent immune activation caused by a Chlamydia trachomatis infection of the fallopian tube.
I, Ohsawa +6 more
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Many sex partners of persons with gonorrhea or chlamydial infections are not treated, which leads to frequent reinfections and further transmission.We randomly assigned women and heterosexual men with gonorrhea or chlamydial infection to have their partners receive expedited treatment or standard referral. Patients in the expedited-treatment group were
Matthew R, Golden +10 more
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[Persistent chlamydial genital infection in Tianjin area: An epidemiological study].
Zhonghua nan ke xue = National journal of andrology, 2018To investigate the epidemic features of persistent genital chlamydial infection (GCI) in Tianjin area.We statistically analyzed the clinical data about the persistent GCI patients received at the Venereal Disease Clinic of Tianjin Medical University General Hospital from 2009 to 2011.A total of 158 patients with persistent GCI were received from ...
Zhi-Chao, Liu +5 more
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