Rac1 regulates the NLRP3 inflammasome which mediates IL-1beta production in Chlamydophila pneumoniae infected human mononuclear cells. [PDF]
Chlamydophila pneumoniae causes acute respiratory tract infections and has been associated with development of asthma and atherosclerosis. The production of IL-1β, a key mediator of acute and chronic inflammation, is regulated on a transcriptional level ...
Julia Eitel +9 more
doaj +1 more source
Analysis of polymorphic membrane protein expression in cultured cells Identifies PmpA and PmpH of Chlamydia psittaci as candidate factors in pathogenesis and immunity to infection [PDF]
The polymorphic membrane protein (Pmp) paralogous families of Chlamydia trachomatis, Chlamydia pneumoniae and Chlamydia abortus are putative targets for Chlamydia vaccine development. To determine whether this is also the case for Pmp family members of C.
Bavoil, Patrik +7 more
core +2 more sources
The atypical pneumonias: The South African context
Community-acquired pneumonia (CAP) is a common clinical presentation in general practice. The prevalence and burden of disease caused by the atypical bacteria (Mycoplasma pneumoniae, Chlamydophila pneumoniae and Legionella pneumophila) are not well ...
A.D. Black
doaj +1 more source
Identification and characterization of a type III secretion system in Chlamydophila psittaci [PDF]
Chlamydiaceae are obligate intracellular Gram-negative bacteria replicating in vacuoles inside eukaryotic cells. It has been proven that most of them possess a type III secretion system (T3SS) allowing them to transfer effector molecules in the host cell.
Beeckman, Delphine Sylvie Anne +4 more
core +4 more sources
Chlamydial infection from outside to inside [PDF]
Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic developmental cycle. Specific interactions with the host cell are crucial for the bacteria's survival and amplification because of the reduced chlamydial genome.
Gitsels, Arlieke +2 more
core +2 more sources
Evaluation of yield of currently available diagnostics by sample type to optimize detection of respiratory pathogens in patients with a community-acquired pneumonia [PDF]
Background: For the detection of respiratory pathogens, the sampling strategy may influence the diagnostic yield. Ideally, samples from the lower respiratory tract are collected, but they are difficult to obtain.
Huijskens, E. (Elisabeth) +4 more
core +6 more sources
Клинико-эпидемиологические закономерности распространения Chlamydophila pneumoniae в воинских коллективах, создание оптимальных схем профилактики инфекции [PDF]
CHLAMYDOPHILA PNEUMONIAE /профВОЕННОСЛУЖАЩИЕРЕСПИРАТОРНЫЕ ИНФЕКЦИИ /профПНЕВМОНИЯ ...
Редненко, В. В.
core +1 more source
Laboratory methods for case finding in human psittacosis outbreaks: a systematic review. [PDF]
Psittacosis outbreak investigations require rapid identification of cases in order to trace possible sources and perform public health risk assessments.
Dijkstra, Frederika +3 more
core +3 more sources
Background Chlamydophila pneumoniae and Mycoplasma pneumoniae are associated with acute exacerbation of bronchial asthma (AEBA). The aim of this study was to evaluate the correlation between these acute bacterial infections and the severity of AEBA ...
Pappalettera Maria +8 more
doaj +1 more source
Microbial aetiology, outcomes, and costs of hospitalisation for community-acquired pneumonia; an observational analysis [PDF]
BACKGROUND: The aim of this study was to investigate the clinical outcome and especially costs of hospitalisation for community-acquired pneumonia (CAP) in relation to microbial aetiology. This knowledge is indispensable to estimate cost-effectiveness of
Ewoudt MW van de Garde +6 more
core +2 more sources

