Pnictogen-Bond-Directed Self-Assembly of Sb and As Cages Enables Partitioning of Organic Reaction Media. [PDF]
Villanueva OH +5 more
europepmc +1 more source
Stable water‐soluble luminescent tris(2,4,6‐trichlorophenyl)methyl (TTM) radicals, TTM‐trisTP3B and TTM‐trisTP9B, were designed and successfully synthesized. They exhibited deep‐red emissions and high photostability in water. TTM‐trisTP3B exhibited dual functionality as a fluorescence imaging (FI) probe and a magnetic resonance imaging (MRI) contrast ...
Kosuke Anraku +6 more
wiley +1 more source
Supercritical Carbon Dioxide-Peracetic Acid Treatment Inactivates Low-Level Bacterial Inocula in Collagen Analogue-Phosphorylcholine Hydrogels while Preserving Functional Properties. [PDF]
Goodarzi H +12 more
europepmc +1 more source
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou +12 more
wiley +1 more source
Spectrophotometric determination of levofloxacin using bromophenol blue: insight into the structure of the formed supramolecular complex. [PDF]
Nashat NW +6 more
europepmc +1 more source
DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Tianru Yang +8 more
wiley +1 more source
From GROMACS Molecular Dynamics Simulations to Electronic Absorption Spectra: A Tutorial for Small Molecules in Organic Solvents. [PDF]
Picarelli C, Raffaini G, Tommasini M.
europepmc +1 more source
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang +11 more
wiley +1 more source
Bioactive screening and molecular docking of phenolics from Stellaria pallida. [PDF]
Selim MT, Elnosary ME, El-Gwaid FSA.
europepmc +1 more source
An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu +7 more
wiley +1 more source

