Results 221 to 230 of about 371,588 (259)

Spatiotemporally Ultrasound‐Controlled Nanoparticles Reprogramming Immunostimulatory Antigen‐Presenting Cancer‐Associated Fibroblasts to Enhance Cancer Immunotherapy

Advanced Science, EarlyView.
We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai, Weikai Sun, Yuxuan Zhao, Daqian Sun, Ting Meng, Yafei Qi, Fengyang Jiang, Jintang Sun, Zhiliang Gao, Dexin Yu   +9 more
wiley   +1 more source

Unveiling the antidiabetic, anti-inflammatory and anti-hemolytic activities of Raphanus sativus leaves through in-vitro and in-silico studies. [PDF]

Sci Rep
Şahin RH, Yalçın E, Çavuşoğlu K, Özkan B.   +3 more
europepmc   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

Fabrication of MOF-Functionalized Silica Monoliths and Their Unique Retention Behavior in HPLC. [PDF]

ACS Omega
Matsubara K, Hosono N, Uemura T, Konishi-Yamada S, Kubo T.   +4 more
europepmc   +1 more source

Bioinspired Ionochromic Neuromorphic Transistors for Robotic Intelligent Perception

Advanced Science, EarlyView.
A bioinspired ionochromic neuromorphic transistor couples synaptic conductance modulation with reversible color change through voltage‐controlled ion doping in P3HT/ion gel, mimicking biological synaptic plasticity, and chameleon‐like color regulation.
Quanxing Yao, Xiaojian Zhu, Runsheng Gao, Qian Jiang, Cui Sun, Yi Du, Xuerong Liu, Lixun Wang, Haolong Li, Yuejun Zhang, Run‐Wei Li   +10 more
wiley   +1 more source

Design, Synthesis, and Biological Activity of (<i>E</i>)-α-Fluorovinylphosphonate-Based Reversible Cathepsin C Inhibitors. [PDF]

J Org Chem
Kaźmierczak M, Bilska-Markowska M, Wiśniewska K, Pawełczak M, Nowak D, Hoffmann M.   +5 more
europepmc   +1 more source

From Energy Deprivation Stress to Catalytic Adaptation of Reductive Dehalogenase TmrA for 1,1-DCA Dechlorination: An Experimental and in Silico Study. [PDF]

Microb Biotechnol
Ren Y, Landers E, Lee M, Manefield M.
europepmc   +1 more source

[1,2]-Carbon to Carbon Silyl Migration for Accessing α-Silyl Alkanals from α-Hydroxy Allyl Silanes. [PDF]

J Org Chem
Singh D, Maloba EW, Maleczka RE.
europepmc   +1 more source

One-pot catalytic oxidation for the synthesis of 2-biphenylbenzoxazoles, benzothiazoles and 1-substituted benzimidazoles: a convenient and efficient strategy. [PDF]

RSC Adv
Ouyang Y, Zhang N, Yang M, Yang H, Jiang B, Xie H, Zhang M.   +6 more
europepmc   +1 more source