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Plasma chlorpropamide: A critical factor in chlorpropamide-alcohol flush

European Journal of Clinical Pharmacology, 1983
The chlorpropamide-alcohol flush (CPAF) phenomenon was quantitatively related to blood levels of acetaldehyde and chlorpropamide in 105 Type II diabetics, of whom 74 had not previously taken the drug and 31 were on chronic treatment. Standardized skin temperature recordings were made with a sensitive probe.
Peter Jerntorp, L O Almer, Hans Ohlin
exaly   +3 more sources

Chlorpropamide Poisoning

Pediatrics, 1968
Clinical signs of hypoglycemia developed in a 3½-year-old boy 24 hours after he had eaten some of the attractively blue-colored chlorpropamide tablets. Low blood sugar values persisted for 4 days after the ingestion concomitant with an increase in serum insulin concentration. On the fifth day, the blood sugar rose to normal levels.
B, Greenberg, C, Weihl, G, Hug
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Chlorpropamide in the Management of Diabetes

Archives of Internal Medicine, 1959
Chlorpropamide is a new oral antidiabetic agent. Its chemical name isN-propyl-N'-(p-chloro-benzenesulfonyl)urea. The structural formula (Fig. 1) is similar to other sulfonamide derivatives which have been observed to have a blood-sugar-lowering effect.
S J, SUGAR, L J, THOMAS, T M, EUGENIO
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