Results 341 to 350 of about 11,449,307 (399)

Thiophene Containing Polycyclic Aromatic Hydrocarbon Monkey Saddles

open access: yesAsian Journal of Organic Chemistry, EarlyView.
A series of thiophene containing polycyclic aromatic hydrocarbon monkey saddles is presented. The core structure was successfully functionalized to tune the optoelectronic properties and furthermore path the way to use these monkey saddles as building block, for example for oligomeric structures as well as organic cage compounds.
Tobias Kirschbaum   +6 more
wiley   +1 more source

Digital welfare‐to‐work in the global south: A case of Indonesian pre‐employment card program

open access: yesAustralian Journal of Social Issues, EarlyView.
Abstract The worldwide movement toward digitisation in public service delivery presents a range of opportunities and risks. The potential benefits include improved efficiency, more consistent service delivery decisions and enhanced responsiveness to citizens' demand.
Phuc Nguyen   +3 more
wiley   +1 more source

A hepatoprotective experiment on taro vegetable (Colocasia esculenta (L.) Schott) flower employing animal models by mitigating oxidative stress

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The antioxidant efficacy of Colocasia esculenta flower’s methanolic extract was assessed using 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic) (ABTS) and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) scavenging assay. The hepatoprotective effect was investigated by assessing liver injury indicators (amino transferase [ALT], aspartate amino transferase [AST],
Mahathir Mohammad   +9 more
wiley   +1 more source

Scale‐Down Analysis of Fouling in Cell Retention Devices for the Continuous Production of Monoclonal Antibodies

open access: yesJournal of Advanced Manufacturing and Processing, EarlyView.
ABSTRACT The use of perfusion bioreactor systems is increasing in biomanufacturing due to their potential for productivity gains, increased facility utilization, and process intensification. Systematic studies on cell retention devices are limited even if these devices are often described as process‐limiting during perfusion.
Delphine Tavernier   +2 more
wiley   +1 more source

Fluoxetine Treatment in Epilepsy of Infancy with Migrating Focal Seizures Due to KCNT1 Variants: An Open Label Study

open access: yesAnnals of Neurology, EarlyView.
Objective Gain‐of‐function (GoF) variants in KCNT1 encoding for potassium channels are associated with different epilepsy phenotypes, including epilepsy of infancy with migrating focal seizures (EIMFS), other early infantile developmental and epileptic encephalopathies, and focal epilepsy.
Marina Trivisano   +13 more
wiley   +1 more source

A Biodegradable Radical Polymer Enables High‐Performance, Physically Transient Organic Memory

open access: yesAngewandte Chemie, EarlyView.
A stable radical polymer with intrinsic memristivity and on‐demand physical transience is presented. We leverage the nonconjugated nature of the radical polymer for a systematic molecular engineering. The polymer enabled a high‐performance organic memristive device comparable to inorganic transient memory devices, now equipped with additional ...
Jaehyoung Ko   +7 more
wiley   +1 more source

Highly Efficient and Selective Photocatalytic CO2 Reduction to Ethanol by Cu4 Clusters with Adjacent Cu Single Atoms Anchored on Carbon Nitride

open access: yesAngewandte Chemie, EarlyView.
A catalyst composed of Cu4 clusters and adjacent Cu single atoms anchored on carbon nitride was prepared via a two‐step calcination process. The synergistic effect between Cu4 clusters and Cu single atoms could lower the C─C coupling energy barrier and make it one of the most efficient catalysts for CO2 to ethanol via photocatalysis.
Zhenguo Guo   +8 more
wiley   +1 more source

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

open access: yesAngewandte Chemie, EarlyView.
AZD0156, an ATM kinase inhibitor in clinical development, shows promising multistage antiplasmodial activity by targeting Plasmodium falciparum phosphatidylinositol 4‐kinase (PfPI4Kβ). With an improved specificity profile relative to other PfPI4Kβ inhibitors and moderate efficacy in a P.
John G. Woodland   +33 more
wiley   +1 more source

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