Results 121 to 130 of about 904,574 (316)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The Choices we Make – A Sliding Doors Moment
, 2014 There are two alternative visions of the future for Australian workers. Which turns out to be true depends on the choices we make over coming years.
Peetz, David Robert
core
DIYmodify Factsheet: CHOICES for HANDRAILS
, 2017 Gives information on some of the many choices of handrails to choose from and why you might choose one over the ...
Barlow, G +1 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Choices that students make between different post-18 routes and whether these choices are effective and reliably informed : review of relevant literature and evidence. Final Report, May 2019 [PDF]
, 2019 Department for Education commissioned the Institute for Employment Research at Warwick University to undertake a review of relevant literature and evidence into choices that students make between different post-18 vocational, academic and technical, and ...
Dickinson, Peter
core
Global EpidemiologyBackground: Although promising effort has been made so far, HIV remains a public health concern. Women in Ethiopia are disproportionately affected by HIV, accounting for a majority of new infections and HIV -related deaths.
Tegene Atamenta kitaw +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Career choices among medical students in Bangladesh
, 2011 SM Moslehuddin Ahmed1, Md Anwarul Azim Majumdar2, Rezina Karim3, Sayeeda Rahman2, Nuzhat Rahman41Department of Community Medicine, Uttara Adhunik Medical College, Dhaka, Bangladesh; 2Department of Clinical Sciences, School of Life Sciences, University of
SM Moslehuddin Ahmed +3 more
core
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source