Results 91 to 100 of about 1,043 (244)

Flap perfusion of superficial split flap design for guided bone regeneration: A case report with ultrasonography

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Effective flap management is crucial for successful bone regeneration procedures. Traditional flap release has been performed by the deep split design; recently, the superficial split design revives for its proposed anatomical and biomechanical advantages.
Oscar Durán‐Garnica   +4 more
wiley   +1 more source

Customized three dimensionally printed palatal stents: A randomized controlled clinical trial

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Soft tissue grafts are commonly used in periodontal surgery around teeth and implants. However, few studies have examined donor‐site pain through patient‐reported outcomes following soft tissue grafting. This study aimed to minimize donor‐site pain during autologous gingival grafting using a three‐dimensionally (3D)‐printed stent ...
Mi‐Seon Goh   +4 more
wiley   +1 more source

Lower AKI Risk and Higher Survival With Microaxial Flow Pump Support During Elective PCI: A Propensity Score‐Matched Study

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Acute kidney injury (AKI) is associated with worse outcomes after percutaneous coronary intervention (PCI). Previous, smaller studies suggested nephroprotective effects of micro‐axial flow pump (mAFP) during PCI. This study aimed to compare renal outcomes of high‐risk PCI with mAFP or intraaortic balloon pump (IABP) support.
Elric Zweck   +10 more
wiley   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović   +11 more
wiley   +1 more source

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba   +7 more
wiley   +1 more source

Sainte-Chapelle

open access: yes
interior, Interior, upper chapel; tribune of the relics, connecting to choir screen, 20084 Boulevard du Palais, 75001 Paris ...
Montreuil, Pierre de   +2 more
core  

Sustainable curriculum innovation through educational design research in conservatoire education

open access: yesThe Curriculum Journal, EarlyView.
Abstract This study reported a four‐year educational design research (EDR) project at a Dutch conservatoire, where researchers and practitioners collaboratively redesigned the Bachelor of Music curriculum. Through iterative, practitioner‐led cycles of exploration, prototyping, implementation, and evaluation, the intervention produced a shared ...
Tamara Rumiantsev   +2 more
wiley   +1 more source

Lincoln Cathedral

open access: yes
Plan ; choir separated from public nave and transept by choir screen ; choir was where plays early were often staged in predawn ...

core  

Unveiling spatial heterogeneity in urban underground space development patterns and mechanisms for differentiated planning: A points of interest‐based study of Shanghai

open access: yesDeep Underground Science and Engineering, EarlyView.
This study investigated the spatial patterns and development mechanisms of urban underground space (UUS) in Shanghai using underground points of interest data. It revealed distinct development mechanisms between the main city and suburbs, highlighting the need for differentiated UUS planning and policies to optimize underground space resources ...
Chenxiao Ma   +3 more
wiley   +1 more source

Associations Between Microbial Depletion and Autonomic Dysregulation in Binge‐Eating Disorder

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The interplay between the gut microbiome and autonomic nervous system remains unexplored in binge‐eating disorder (BED). We aimed to explore specific microbial alterations in BED and examine their potential association with cardiac vagal tone as a distinct bio‐behavioral phenotype.
Shuang Liang   +4 more
wiley   +1 more source

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