Results 101 to 110 of about 28,815 (254)

Anti‐Integrin αvβ6 Autoantibodies as Diagnostic and Monitoring Biomarkers for Pediatric‐Onset Primary Sclerosing Cholangitis

Hepatology Research, EarlyView.
Levels of anti‐integrin αvβ6 antibodies were significantly higher in pediatric‐onset primary sclerosing cholangitis (PSC) than in autoimmune hepatitis (AIH) and may reflect disease activity. These antibodies may serve as a novel biomarker for distinguishing PSC from AIH and for monitoring disease progression.
Yukako Maeda, Shuichiro Umetsu, Eitaro Hiejima, Mitsuyoshi Suzuki, Itaru Iwama, Takeshi Kimura, Sonoko Kondo, Ayano Inui, Hiroki Kondou, Tatsuya Okamoto, Takashi Ito, Hiroyuki Shirahase, Kazushi Izawa, Takahiro Yasumi, Takeshi Kuwada, Masahiro Shiokawa, Hiroshi Seno, Junko Takita   +17 more
wiley   +1 more source

Secondary sclerosing cholangitis in patients with drug-induced liver injury.

, 2015
To access publisher's full text version of this article click on the hyperlink at the bottom of the pageSecondary sclerosing cholangitis has clinical features similar to primary sclerosing cholangitis but originates from a known pathological entity ...
Gardarsdottir, Marianna, Thorisson, Hjalti M, Bergmann, Ottar M, Björnsson, Einar S, Gudnason, Hafsteinn O, Olafsson, Sigurdur, Björnsson, Helgi K   +6 more
core   +1 more source

Primary sclerosing cholangitis

Autoimmunity Reviews, 2003
Primary sclerosing cholangitis (PSC) is a fibrosing disease of the intra- and extra-hepatic bile ducts, and is closely associated with inflammatory bowel disease. It is immune mediated, rather than being a classical autoimmune disease. A range of immune abnormalities have been demonstrated in PSC, in particular the findings of a range of autoantibodies,
Cullen, S, Chapman, R
openaire   +2 more sources

Annual magnetic resonance cholangiopancreatography surveillance outcomes in individuals with primary sclerosing cholangitis

Internal Medicine Journal, EarlyView.
Abstract Background Annual surveillance for cholangiocarcinoma using magnetic resonance cholangiopancreatography (MRCP) has been recommended in primary sclerosing cholangitis (PSC) to improve the associated dismal outcomes. However, data are limited. Aims To compare the outcomes of surveillance versus non‐surveillance in patients with PSC.
Gary Dezhi Zhang, Chloe Attree, Nazneen Irani, Jonathan Tibballs, John Ferguson, Luis Calzadilla Bertot, Michael Wallace, Briohny Smith, George Garas, Gary Jeffrey, Leon Anton Adams, Gerry MacQuillan   +11 more
wiley   +1 more source

Primary sclerosing cholangitis: diagnostic and management challenges

, 2017
Sanjeev Sirpal,1 Natasha Chandok2 1Department of Medicine, Centre Hospitalier de l’Université de Montréal (CHUM), University of Montreal, Montreal, QC, 2Department of Medicine, University of Western Ontario, London, ON, Canada ...
Sirpal S, Chandok N
core  

Pathogenesis of primary sclerosing cholangitis

, 2011
Primary sclerosing cholangitis (PSC) represents a chronic cholestatic liver disease with fibroobliterative sclerosis of intra- and/or extrahepatic bile ducts, eventually leading to biliary cirrhosis.The association with human leukocyte antigen (HLA) and ...
Fickert, Peter, Trauner, Michael, Peter Fickert, Michael Trauner, Marion J. Pollheimer, Halilbasic, Emina, Emina Halilbasic, Pollheimer, Marion J.   +7 more
core   +1 more source

The role of neutrophils in the pathophysiology of inflammatory bowel diseases

Periodontology 2000, EarlyView.
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens, Ekin Yay‐Kus, Rafael Scaf de Molon, Viorelia Stoica, Peter Rimmer, Josefine Hirschfeld, Asif Jilani Iqbal, Tariq Iqbal, Iain Chapple   +8 more
wiley   +1 more source

Ketamine-Induced Sclerosing Cholangitis Associated With Early Inflammatory Bowel Disease During Chronic Topical Ketamine Use

Gastro Hep Advances
Ketamine-induced sclerosing cholangitis has been described with chronic intranasal and intravenous use. Our case follows chronic topical use for peripheral neuropathy.
Gerond Lake-Bakaar, Benjamin Milgrom, Clark Kulig, Andrea K. Sotelo, Joselle Speirs, Alexandra Meihofer   +5 more
doaj   +1 more source

ARC in Critical Ill OLT Recipients: True Prevalence, Risk Factors, and Impact on Early Aggressive PK/PD Target Non‐Attainment of CI Beta‐Lactam Therapy for Posttransplant Gram‐Negative Infections

Transplant Infectious Disease, EarlyView.
Augmented renal clearance (ARC) represents a quite prevalent condition among critical orthotopic liver transplant recipients (23.2%). ARC is associated with different demographics and clinical features and significantly affects the attainment of aggressive beta‐lactams pharmacokinetic/pharmacodynamic targets despite the administration of standard ...
Milo Gatti, Riccardo De Paola, Matteo Rinaldi, Cristiana Laici, Antonio Siniscalchi, Pierluigi Viale, Federico Pea   +6 more
wiley   +1 more source

Association of extraintestinal manifestations of inflammatory bowel disease in a province of western Hungary with disease phenotype: Results of a 25-year follow-up study

, 2003
AIM: IBD is a systemic disease associated with a large number of extraintestinal manifestations (EIMs). Our aim was to determine the prevalence of EIMs in a large IBD cohort in Veszprem Province in a 25-year follow-up study.
Dávid, Gyula, Balogh, Zsuzsanna, Tollas, Árpád, Lakatos, Péter László, Pandur, Tünde, Kuronya, Pál, Lakatos, László   +6 more
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