Results 101 to 110 of about 44,324 (216)

Methodological overview of systematic reviews to establish the evidence base for emergency general surgery [PDF]

open access: yes, 2017
BACKGROUND: The evidence for treatment decision‐making in emergency general surgery has not been summarized previously. The aim of this overview was to review the quantity and quality of systematic review evidence for the most common emergency surgical ...
  +15 more
core   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, Volume 1, Issue 3, Page 322-358, December 2025.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Percutaneous cholecystostomy as a nonsurgical option for treatment of acute cholecystitis in elderly patients

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2018
Objectives: To evaluate the efficacy and safety of percutaneous cholecystostomy (PC) in management of acute cholecystitis in elderly patients. Methods: Retrospective study of elderly patients (age ≥ 60 years) undergoing Ultrasound-guided PC for acute ...
Amr Mahmoud Abdel Samad   +2 more
doaj   +1 more source

Choosing the optimal timing of laparoscopic cholecystectomy for acute calculous cholecystitis with peripancreatic infiltrate

open access: yesУкраїнський журнал клінічної хірургії
Objective. To determine the optimal timing of laparoscopic cholecystectomy in acute calculous cholecystitis with peripancreatic infiltrate. Materials and methods.
I. L. Kyazimov   +5 more
doaj   +1 more source

Efficacy and safety in tirzepatide‐treated Korean adults with type 2 diabetes—A post hoc analysis of SURPASS‐AP‐combo and SURPASS‐3

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 7110-7122, December 2025.
Abstract Aims This post hoc analysis assessed the efficacy and safety data in tirzepatide‐treated Korean patients with type 2 diabetes (T2D). Materials and Methods Data specifically from Korean patients treated with tirzepatide 5, 10, or 15 mg in the multicentre, randomised, open‐label, parallel‐group, phase 3 trials SURPASS‐AP‐Combo and SURPASS‐3 were
Byung Wan Lee   +11 more
wiley   +1 more source

Report of a case with gallbladder torsion

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2006
BACKGROUND AND OBJECTIVE: Gallbladder torsion is a rare condition of acute abdomen that can lead to acute cholecystitis and gallbladder gangrene. Preoperative diagnosis of this condition is usually difficult and in the most cases, diagnosis achieved at ...
SR Hashemi
doaj  

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

open access: yesObesity Reviews, Volume 26, Issue 12, December 2025.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin   +6 more
wiley   +1 more source

Improving Patient Decision-Making in Health Care [PDF]

open access: yes, 2011
Outlines regional variations within Minnesota in rates of patients with similar conditions receiving elective surgery, the concept of shared decision making, treatment choices for eight conditions, and steps for ensuring patients make informed ...
David C. Goodman   +5 more
core  

Acute Acalculous Cholecystitis due to Salmonella Enteritidis in a Child with Influenza A (H1N1)v [PDF]

open access: yes, 2014
A colecistite aguda acalculosa é uma entidade pouco frequente na idade pediátrica e uma complicação rara da enterocolite por salmonelas não tifóides. A co-infecçãocom o virus influenza A (H1N1)v nunca foi previamente descrita.
Brito, MJ, Gouveia, C, Regala, J
core  

ACALCULOUS CHOLECYSTITIS IN A PATIENT WITH PLASMODIUM FALCIPARUM MALARIA AND CYTOMEGALOVIRUS INFECTION [PDF]

open access: yes, 2017
Acalculous cholecystitis is a syndrome of gallbladder inflammation without gallstones, recognized within the setting of critically ill patients. Acalculous cholecystitis associated with infectious agents is reported in the literature to be rare.
Cascio, A.   +6 more
core  

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