Results 61 to 70 of about 43,781 (217)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Comparison of the Role of High Neutrophil to Lymphocyte Ratio with Leukocytosis in Diagnosing Acute Cholecystitis

open access: yesPakistan Armed Forces Medical Journal, 2023
Objective: To compare the diagnostic accuracy of high neutrophil-to-lymphocyte ratio levels versus leukocytosis in detecting acute cholecystitis. Study Design: Cross-sectional validation study.
Muhammad Umair Khalid   +5 more
doaj   +1 more source

Safety and Effectiveness of Cholecystectomy and Endoscopic Retrograde Cholangiopancreatography in Biliary Pancreatitis During Pregnancy: BORN Study

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Biliary acute pancreatitis (AP) during pregnancy is a challenging situation, and current guidelines for AP, pregnancy care, and surgery do not specifically address its management. This study investigated the safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopancreatography (ERCP) during pregnancy in AP ...
Dorottya Tarján   +35 more
wiley   +1 more source

Quantitative Analysis of Troponin I Serum Values in Patients with Acute Cholecystitis [PDF]

open access: yes, 2012
The diagnosis and staging of acute cholecystitis, upon a lot of diagnostic methods and some scoring systems, is still a great clinical problem. The aim of the study was to investigate if serum Troponin I is elevated in patients with acute cholecystitis ...
Ivo Sjekavica   +10 more
core   +1 more source

An Early Holiday Surprise: Cholecystitis Wrapped in Takotsubo Cardiomyopathy [PDF]

open access: yes, 2020
This is a novel case report of a 44-year-old woman who presented to the emergency department with epigastric pain wrapping around to her back. She had no risk factors for cardiac disease, but her initial electrocardiogram (ECG) showed a Wellens syndrome ...
Gould, Kevin   +2 more
core  

Impact of a Thinner Snare Wire With Optimal Electrosurgical Unit Settings on the Risk of Delayed Bleeding After Endoscopic Papillectomy: A Propensity Score‐Matched Analysis (With Video)

open access: yesDigestive Endoscopy, EarlyView.
ABSTRACT Objectives The indications for endoscopic papillectomy (EP) have expanded. However, post‐procedural adverse events remain high. We performed ex vivo and clinical studies to determine the usefulness of a thinner snare wire (TSW) for preventing delayed bleeding after EP.
Kenjiro Yamamoto   +13 more
wiley   +1 more source

Management of Acute Cholecystitis

open access: yesThe Korean Journal of Gastroenterology, 2018
Acute cholecystitis is a common serious complication of gallstones. The reported mortality of acute cholecystitis is approximately 3%, but the rate increases with age or comorbidity of the patient. If appropriate treatment is delayed, complications can develop as a consequence with a grave prognosis.
Seung Ok Lee, Sung Kyun Yim
openaire   +4 more sources

Acute Cholecystitis Reduces Interstitial Cells of Cajal in Porcine Gallbladder Through Decreased mRNA Synthesis

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Acute cholecystitis is a common gastrointestinal disorder, often characterized by acute cholecystitis with gallbladder motility disorder.
Zhen-peng Huang, Hu Qiu, Bao-ping Yu
doaj   +1 more source

Acute Acalculous Cholecystitis Associated with Epstein–Barr Infection: A Case Report and Review of the Literature

open access: yesCase Reports in Medicine, 2020
The most common cause of acute cholecystitis (ACC) is cholelithiasis. Acute acalculous cholecystitis (AAC) is well documented in the literature related with critical illness, but viral causes such as cytomegalovirus (CMV) and Epstein–Barr virus (EBV ...
Konstantinos Ntelis   +6 more
doaj   +1 more source

Efficacy and safety in tirzepatide‐treated Korean adults with type 2 diabetes—A post hoc analysis of SURPASS‐AP‐combo and SURPASS‐3

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims This post hoc analysis assessed the efficacy and safety data in tirzepatide‐treated Korean patients with type 2 diabetes (T2D). Materials and Methods Data specifically from Korean patients treated with tirzepatide 5, 10, or 15 mg in the multicentre, randomised, open‐label, parallel‐group, phase 3 trials SURPASS‐AP‐Combo and SURPASS‐3 were
Byung Wan Lee   +11 more
wiley   +1 more source

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