Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
ABSTRACT Background Differentiated thyroid carcinoma (DTC) is typically managed surgically with favourable outcomes. However, surgery may have dire consequences when the tumour invades critical structures. Neoadjuvant therapy with tyrosine kinase inhibitors (TKIs) has emerged as a potential strategy to improve resectability and reduce morbidity in ...
Alexandra Dorman +15 more
wiley +1 more source
Cholecystitis in older patients following hip fracture: a case series and literature review [PDF]
Yuan Yuan +4 more
openalex +1 more source
Abstract Aims Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are widely used for type 2 diabetes mellitus and obesity, with once‐weekly dosing that supports adherence. However, injection‐site reactions (ISRs) and dermatologic events have been recognised, ranging from mild local events to rare systemic hypersensitivity reactions that may cause ...
Shifa Taj +6 more
wiley +1 more source
Pneumomediastinum as a complication of emphysematous cholecystitis: Case report
Background Emphysematous cholecystitis is a variant of acute cholecystitis which is generally caused by gas-forming organisms. Emphysematous cholecystitis may cause gas spreading within the subcutaneous tissue, peritoneal cavity and retroperitoneum. Case
Delgado-Plasencia Luciano +3 more
doaj +1 more source
Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies
ABSTRACT Hematologic malignancies represent the most common cancers in children. While the mainstays of treatment are chemotherapy and potentially hematopoietic stem cell transplant, minimally invasive surgery (MIS) has a role in the diagnosis and management of complications related both to disease and therapy as well as common pediatric surgical ...
Alejandro Chara +3 more
wiley +1 more source
Sutimlimab in Patients With Cold Agglutinin Disease (CAD): Results From a Managed Access Program
ABSTRACT Cold agglutinin disease (CAD) is a low‐grade lymphoproliferative disorder accounting for 15%–30% of patients suffering from autoimmune hemolytic anemias. The clonal B cells produce autoantibodies primarily of the IgM‐κ class that cause agglutination of red blood cells (RBCs) at temperatures ≤ 37°C and activate the classical complement pathway ...
Sandra Maria Frey +5 more
wiley +1 more source
Acute cholecystitis and helminthic infestation
Acute cholecystitis is an important acute medical problem, so acute disorder of the gall bladder requires good clinical management. There are several etiologies of acute cholecystitis.
Pathum Sookaromdee, Viroj Wiwanitkit
doaj +1 more source
Active Gallbladder Lavage Using a Double-pigtail Plastic Stent Delivery System During Endoscopic Ultrasound-guided Gallbladder Drainage (With Video). [PDF]
Endoscopic ultrasound‐guided gallbladder drainage using a double‐pigtail plastic stent (DPPS) harbors the risk of bile leakage and pneumoperitoneum through the anastomosis site. When the inner sheath of the DPPS system is retracted halfway back into the stent, multiple side holes emerge on the stent end, which accelerates the active gallbladder lavage.
Ban T +7 more
europepmc +2 more sources
Pleural empyema caused by dropped gallstones after laparoscopic cholecystectomy for acute cholecystitis: a case report [PDF]
Aya Tokuda +11 more
openalex +1 more source

