Results 101 to 110 of about 322,595 (355)

Cholera Epidemic — Lusaka, Zambia, October 2017–May 2018

open access: yesMMWR. Morbidity and mortality weekly report, 2018
On October 6, 2017, an outbreak of cholera was declared in Zambia after laboratory confirmation of Vibrio cholerae O1, biotype El Tor, serotype Ogawa, from stool specimens from two patients with acute watery diarrhea.
N. Sinyange   +42 more
semanticscholar   +1 more source

Populations Addressed in Vaccines Approved via the European Medicines Agency

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Therapeutic and prophylactic agents require robust evidence before patient use. Randomized controlled trials are essential for evaluating safety and efficacy but often exclude specific populations that are also targets for the intervention. This study assessed which populations are included in vaccine registration studies and/or addressed in label ...
Débora D. Gräf   +3 more
wiley   +1 more source

Carbapenem resistance in Acinetobacter baumannii and other Acinetobacter spp. causing neonatal sepsis: focus on NDM-1 and its linkage to ISAba125

open access: yesFrontiers in Microbiology, 2016
Carbapenem-resistant determinants and their surrounding genetic structure were studied in Acinetobacter spp. from neonatal sepsis cases collected over 7 years at a tertiary care hospital. Acinetobacter spp.
Somdatta Chatterjee   +7 more
doaj   +1 more source

Eff ectiveness of reactive oral cholera vaccination in rural Haiti: a case-control study and bias-indicator analysis [PDF]

open access: yes, 2015
Background Between April and June, 2012, a reactive cholera vaccination campaign was done in Haiti with an oral inactivated bivalent whole-cell vaccine.
B Harris, Jason   +10 more
core   +1 more source

Exploring Droughts and Floods and Their Association with Cholera Outbreaks in Sub-Saharan Africa: A Register-Based Ecological Study from 1990 to 2010

open access: yesAmerican Journal of Tropical Medicine and Hygiene, 2018
. Cholera outbreaks in Africa have been attributed to both droughts and floods, but whether the risk of a cholera outbreak is elevated during droughts is unknown. We estimated the risk of cholera outbreaks during droughts and floods compared with drought-
A. Rieckmann   +4 more
semanticscholar   +1 more source

The upside of epilepsy: Theories of an evolutionary paradox

open access: yesEpilepsia Open, EarlyView.
Abstract The persistence of common, heritable conditions, like epilepsy, that are associated with reduced reproductive fitness is an evolutionary paradox. Endogenous analgesic, anti‐depressant, and inflammatory mechanisms able to repair compromised functions can offer advantages in unexpected crises.
Alyssa Ailion   +3 more
wiley   +1 more source

Intranasal immunization of mice with chimera of Salmonella Typhi protein elicits protective intestinal immunity

open access: yesnpj Vaccines
Development of safe, highly effective and affordable enteric fever vaccines is a global health priority. Live, oral typhoid vaccines induce strong mucosal immunity and long-term protection, but safety remains a concern.
Suparna Chakraborty   +8 more
doaj   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

open access: yesExploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang   +4 more
wiley   +1 more source

Emergence of Azithromycin Resistance Mediated by Phosphotransferase-Encoding mph(A) in Diarrheagenic Vibrio fluvialis

open access: yesmSphere, 2019
The azithromycin resistance conferred by phosphotransferase is encoded in the gene mph(A). This gene has been discovered in and reported for many bacterial species.
Goutam Chowdhury   +5 more
doaj   +1 more source

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