Results 201 to 210 of about 329,312 (342)

Fmr1 knockout disrupts multiple intrinsic properties via reduced HCN channel activity in mediodorsal thalamocortical neurons

open access: yesExperimental Physiology, EarlyView.
Abstract The neurodevelopmental disorder fragile X syndrome (FXS) results from hypermethylation of the FMR1 gene, which prevents production of the FMRP protein. FMRP modulates the expression and function of a variety of proteins, including voltage‐gated ion channels, such as hyperpolarization‐activated and cyclic nucleotide‐gated (HCN) channels, which ...
Gregory J. Ordemann   +3 more
wiley   +1 more source

Evaluating the Potential of ChatGPT to Support Climate Risk and Adaptation Assessment

open access: yesClimate Resilience and Sustainability, Volume 4, Issue 2, December 2025.
Scaling up adaptation is essential for addressing climate risks, but there are no globally applicable, sector‐based inventories of adaptation options. Assistive technologies like ChatGPT can help with the rapid scoping of climate risks, adaptation actions, costs and benefits and flag potential maladaptation. Adaptation measures identified for national (
Robert L. Wilby
wiley   +1 more source

What Does a Climate‐Resilient Rural Water Supply System Look Like? An Interdisciplinary Approach to Climate Resilience Mapping in Nepal

open access: yesClimate Resilience and Sustainability, Volume 4, Issue 2, December 2025.
The climate resilience mapping framework (Lower left) was applied in the hill district of Nepal (upper left) to map Rural Water Supply Systems (right) ABSTRACT Climate change significantly affects the water, sanitation, and hygiene (WASH) services, especially in rural areas of developing countries like Nepal.
Santosh Nepal   +6 more
wiley   +1 more source

Fowl Cholera (Cholera Gallinarum)

open access: bronze, 1908
Jan Willems, Victor Fortier
openalex   +1 more source

Studies on the Virus of Hog Cholera [PDF]

open access: green, 1913
W King, F. W. Baeslack, G. L. Hoffmann
openalex   +1 more source

Climate Change and Impacts on Human Health: An Experience of Coastal Region People in Bangladesh

open access: yesClimate Resilience and Sustainability, Volume 4, Issue 2, December 2025.
This study examines the impacts of climate change on the physical and mental health of coastal communities in Bangladesh. Using a mixed‐methods approach with 280 participants, 52.5% of respondents reported injuries, and 35% experienced anxiety and depression; the research identifies significant strong correlations both for natural and man‐made ...
Mohammad Shaheen Alam   +5 more
wiley   +1 more source

Antitumor Compounds From Halophilic Streptomyces violaceorubidus M4 Against Triple‐Negative Breast Cancer

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
The antitumor effects of the halophilic Streptomyces violaceorubidus M4 extract on triple‐negative breast cancer, highlighting its selective cytotoxicity and apoptosis‐inducing properties. Key findings include the identification of bioactive compounds and their impact on apoptosis‐related gene expression, as well as significant reductions in tumor cell
Atousa Zia   +3 more
wiley   +1 more source

Analysis of antimicrobial resistance patterns and genetic mutations in Helicobacter pylori from West Bengal, India depicting escalating clarithromycin and high levofloxacin resistance

open access: yesGut Pathogens
Background The growing resistance of Helicobacter pylori (H. pylori) to antibiotics poses a significant global health challenge, particularly in developing regions where infection rates are high, and routine antibiotic susceptibility surveillance is ...
Sangita Paul   +4 more
doaj   +1 more source

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