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Small molecule inhibitor targets OmpV to treat pandemic Vibrio cholerae infection. [PDF]

open access: yesNat Commun
Liu R   +13 more
europepmc   +1 more source

Rethinking cholera diagnostic test performance, interpretation, and evaluation: a field-based latent-class analysis in Bangladesh.

open access: yesLancet Microbe
Perez-Saez J   +14 more
europepmc   +1 more source
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Cholera

Lancet, The, 2022
Cholera was first described in the areas around the Bay of Bengal and spread globally, resulting in seven pandemics during the past two centuries. It is caused by toxigenic Vibrio cholerae O1 or O139 bacteria. Cholera is characterised by mild to potentially fatal acute watery diarrhoeal disease.
Suman Kanungo   +2 more
exaly   +3 more sources

Cholera

Lancet, The, 2004
Intestinal infection with Vibrio cholerae results in the loss of large volumes of watery stool, leading to severe and rapidly progressing dehydration and shock. Without adequate and appropriate rehydration therapy, severe cholera kills about half of affected individuals.
David A Sack
exaly   +3 more sources

Vibrio cholerae: Cholera toxin

The International Journal of Biochemistry & Cell Biology, 2007
The bacterial protein toxin of Vibrio cholerae, cholera toxin, is a major agent involved in severe diarrhoeal disease. Cholera toxin is a member of the AB toxin family and is composed of a catalytically active heterodimeric A-subunit linked with a homopentameric B-subunit.
vanden Broeck, Davy   +2 more
openaire   +3 more sources

Cholera

2003
Few diseases invoke public fear as readily as cholera. In its most severe state, cholera can cause death from hypotensive shock within 12 h of the first symptom. Cholera typically occurs in epidemics, spreading rapidly within the community, especially if hygeinic conditions are poor.
T J, Barrett, D N, Cameron
openaire   +2 more sources

Cholera

Primary Care Update for OB/GYNS, 2001
Cholera, an infectious disease caused by Vibrio cholerae, is primarily transmitted by ingestion of contaminated food or water. In severe cases, cholera may lead to severe dehydration, metabolic acidosis, and ultimately, hypovolemic shock and death. The diagnosis is confirmed by identification of V. cholerae in a stool specimen.
openaire   +2 more sources

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