Results 181 to 190 of about 72,576 (226)
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Preclinical pharmacology of cholera toxin

Cancer Chemotherapy and Pharmacology, 1995
Cholera toxin was selected for pharmacologic evaluation by the National Cancer Institute on the basis of antiproliferative activity against small-cell and non-small-cell lung-cancer cell lines. A feature common to the sensitive cell lines was abundant expression of GM1 ganglioside, the cellular receptor for cholera toxin.
J M, Reid   +3 more
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Heterogeneity of purified cholera toxin

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1977
The heterogeneity of Vibrio cholerae toxin, obtained from culture filtrates in homogeneous form by gel filtration and preparative disc gel electrophoresis has been studied. By means of disc electrophoresis on polyacrylamide gel cholera toxin was separated into three forms designated I (5%), II (15%) and III (80%). The toxic activity, amino acid content
L G, Roda   +6 more
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Cholera toxin inhibits interferon action

Biochemical and Biophysical Research Communications, 1976
Abstract Cholera toxin added together with interferon inhibited the establishment of antiviral activity in mouse L-cells. Cholera toxin has no effect on antiviral activity established before its addition; however, treatment of cells with the toxin before addition of interferon also inhibited the establishment of antiviral activity.
R M, Friedman, L D, Kohn
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Crystalline Cholera Toxin and Toxoid

Science, 1972
The exo-enterotoxin of Vibrio cholerae has been obtained in crystalline form. A solution of the crystalline protein was equal in potency to the parent pure toxin in both choleragenicity and skin reactivity. Crystals of the natural toxoid, choleragenoid, resemble those of the toxin in appearance.
R A, Finkelstein, J J, LoSpalluto
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Nanotransportation system for cholera toxin in Vibrio cholerae 01

Medical Molecular Morphology, 2009
Vibrio cholerae (V. cholerae) cholera toxin (CT), which causes a severe watery diarrheal illness, is secreted via the type II secretion machinery; it remains unclear, however, how this toxin is transported toward the machinery. In this study, we determined that the pH-dependent intrabacterial transport system correlates with the priming of CT secretion
Hiroaki, Aoki   +7 more
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Distribution of genes encoding cholera toxin, zonula occludens toxin, accessory cholera toxin, and El Tor hemolysin Vibrio cholerae of diverse origins

Microbial Pathogenesis, 1995
A large collection of 1154 strains of Vibrio cholerae of diverse origins including serogroups 01 and 0139 and those belonging to the non-01 and non-0139 (non-01:non-0139) serogroups were examined with a battery of DNA probes specific for cholera toxin (CT), zonula occludens toxin (ZOT), accessory cholera toxin (ACE) and El Tor hemolysin (HLY) to ...
H, Kurazono   +6 more
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Protection of rats against cholera toxin and cholera-like enterotoxins by immunization with enteric-coated cholera toxin

Annals of Tropical Paediatrics, 1986
Pure cholera toxin (CT) given as a booster in enteric-coated tablets to rats produced a humoral and intestinal immune response similar to the result of instilling the boosting dose of CT directly into the duodenum. This method protects the antigen against gastric acid and allows delivery of the immunogen to intestinal mucosa, an essential step in ...
C S, Bundell   +3 more
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Cholera Toxin

RCSB Protein Data Bank, 2005
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