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New cholera vaccines

Vaccine, 1989
Development of improved cholera vaccines has progressed rapidly in recent years. An oral killed vaccine, designed to evoke antibacterial as well as antitoxic intestinal immunity, has proved to be completely safe and to protect against cholera for at least 3 years.
David A. Sack   +4 more
openaire   +3 more sources

Cholera Vaccines

1992
The currently licensed parenteral cholera vaccine has not been a useful public health tool in the control of cholera. Building on the knowledge that primary infection offers significant protection against reinfection and that mucosal immunity mediates this protection, several oral cholera vaccines have been developed. These vaccine candidates or future
Carol O. Tacket   +2 more
openaire   +3 more sources

Vaccines for preventing cholera

2001
Oral cholera vaccines (either killed whole cell or live recombinant vaccines) are newer alternatives to the parenteral vaccines which have been thought to confer only moderate and short-term immunity.The objective of this review was to assess the effect of cholera vaccines in preventing cases of cholera and preventing deaths.We searched the Cochrane ...
Mark Pratt   +4 more
openaire   +4 more sources

Vibrio cholerae Vaccines

Clinical Infectious Diseases, 1989
Several approaches to the development of a safe and effective vaccine against Vibrio cholerae are currently being pursued. These candidate vaccines include (1) live V. cholerae strains attenuated by recombinant DNA techniques; (2) killed whole V. cholerae organisms plus purified cholera enterotoxin B subunit; and (3) cloned V.
openaire   +3 more sources

Stability of cholera and typhoid vaccines

Journal of Biological Standardization, 1979
Fluid plain and adsorbed and freeze-dried cholera and tyhpoid vaccines of different composition were examined for thermostability by potency testing (by active mouse protection tests) after exposure to 37 degrees C for 1, 2, 3, 4, 8 and 12 weeks. Loss of potency was evaluated by comparison with samples stored at 4 degrees C.
J. Zsidai, I. Joó
openaire   +3 more sources

Vaccinating against cholera

Nursing Standard, 1990
Vaccination against cholera is being over-prescribed and may lead to a false sense of security.
openaire   +2 more sources

No Vaccines in the Time of Cholera [PDF]

open access: possibleScience, 2010
The threat of a major cholera epidemic looms over flood-stricken Pakistan. So why is a new, relatively cheap vaccine unlikely to make a difference?
openaire   +1 more source

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