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Bivalent Cholera and Typhoid Vaccine
Drugs, 1999The live attenuated vaccine strains Vibrio cholerae CVD 103-HgR and Salmonella typhi Ty21a can be combined into an oral bivalent vaccine without compromising the immunogenicity of the individual vaccine strains. Seroconversion rates of 87 to 94% for Inaba vibriocidal antibodies and 72 to 91% for anti-S.
Stuart Noble, Rachel H. Foster
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The first British reference preparations of cholera vaccine (Inaba) and of cholera vaccine (Ogawa)
Journal of Biological Standardization, 1977Abstract An international collaborative study was undertaken to assess the suitability of a preparation of cholera vaccine (Inaba) and one of cholera vaccine (Ogawa) to serve as British reference preparations. Eight laboratories participated in the study.
Valerie Seagroatt, Annette W. Ford
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Molecular design of cholera vaccines
Vaccine, 1992Cholera is still a serious public health problem in developing countries, particularly those in tropical regions. This has stimulated considerable research into the molecular analysis of pathogenesis resulting in the identification of a number of critical components required for both colonization of the gut mucosa and the disease symptoms.
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Recombinant Live Cholera Vaccines
, 1994This chapter reviews developments and progress in the use of recombinant bacteria as live oral cholera vaccines. The extent to which a prior clinical infection with wild-type enterotoxigenic Vibrio cholerae O1 stimulates protection against cholera in the
M. Levine, Carol O. Jacket
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Embracing Oral Cholera Vaccine — The Shifting Response to Cholera
New England Journal of Medicine, 2014Despite evidence of the safety and efficacy of oral cholera vaccines, they were not included in the prevention package during the 2010 Haitian cholera epidemic. But some major obstacles to the use of OCVs in cholera outbreaks have since been overcome.
Vanessa Rouzier, Jean W. Pape
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Public Health Considerations for the Use of Cholera Vaccines in Cholera Control Programs
, 1994Conventional parenteral cholera vaccines have largely been abandoned as public health tools, and recent studies have elucidated the probable reason for their poor performance.
J. Clemens, D. Spriggs, D. Sack
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TLR2, but not TLR4, plays a predominant role in the immune responses to cholera vaccines
Journal of Leukocyte Biology, 2015J. Yang+9 more
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