Results 101 to 110 of about 89,189 (328)

Canine liver transplantation under nva cyclosporine versus cyclosporine [PDF]

, 1986
The immunosuppressive qualities and other features of a new cyclosporine (CsA) analogue, Nva 2-cyclosporine (Nva 2-CsA) were examined using canine orthotopic liver allografts.
DeWolf, A, Kam, I, Lynch, S, Porter, KA, Starzl, TE, Todo, S, Venkataramanan, R   +6 more
core   +1 more source

Bile Acids as Selective Gatekeepers of Dietary Lipid Absorption: Mechanistic Insights and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Their work provides evidence in murine models that the bile acid pool may function as a tunable filter whose selectivity for different fatty acids depends on bile acid concentration and composition. This framework suggests a selective decoupling of the absorption of excessive saturated fatty acids (SFAs) from that of beneficial polyunsaturated
Hao Wang, Yue Yang, Yulong Zhang, Yinling Li, Xuemei Ma, Haitao Wang   +5 more
wiley   +1 more source

Assessment of aspartate aminotransferase to Platelet Ratio Index and Fibrosis-4 Index score on women with intrahepatic cholestasis of pregnancyAJOG Global Reports at a Glance

AJOG Global Reports
BACKGROUND: Intrahepatic cholestasis of pregnancy is a pregnancy-related liver condition that is characterized by elevated liver function tests and/or bile acids in the presence of pruritis.
Maria Cemortan, PhD, Corina Iliadi-Tulbure, PhD, Irina Sagaidac, PhD, Olga Cernetchi, PhD   +3 more
doaj   +1 more source

Obeticholic acid for the treatment of primary biliary cholangitis in adult patients: clinical utility and patient selection. [PDF]

, 2016
Primary biliary cholangitis (PBC), previously known as primary biliary "cirrhosis", is a rare autoimmune liver disease characterized by the hallmark autoantibodies to mitochondrial antigens and immune-mediated destruction of small bile duct epithelial ...
Bowlus, Christopher L
core   +3 more sources

Breastmilk and medium‐chain triglyceride supplementation: Retrospective study on outcomes in biliary atresia infants after Kasai

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Does breastmilk with medium‐chain triglycerides (MCT) after Kasai support growth and improve surgical outcomes? Abstract Objective To relate post‐surgical feeding regimens to growth and surgical outcomes in children with biliary atresia (BA) after hepato‐portoenterostomy (Kasai).
Thora Wesenberg Helt, Ruben H. de Kleine, Lars Søndergaard Johansen, Tietie Dijkstra, Jan B. F. Hulscher, Henkjan J. Verkade, Vibeke Brix Christensen   +6 more
wiley   +1 more source

Case Report: Progressive Cholestasis: Severe Phenotype of MEGDEL Syndrome With SATB2-Associated Syndrome

, 2021
Yajie Su, Hui Zhang, Huijun Wang, Bingbing Wu, Jiao Yang, Wenhao Zhou, Long Li   +6 more
openalex   +1 more source

Liver disease in Shwachman‐Diamond syndrome: A comprehensive characterization across the age spectrum

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Shwachman‐Diamond syndrome (SDS) is an inherited bone marrow failure disorder, and its hepatic phenotype is poorly defined. Our objective was to systematically characterize the prevalence, features, and outcomes of liver injury in a multicenter SDS cohort. Methods Retrospective registry study of 171 patients with biallelic Shwachman‐
Jane Koo, Diana Schwarz, Meghan Haney, Juan Putra, Jaeson Kim, Leah Cheng, Elizabeth Korn, Sarah Steltz, Lois Schwarz, Sara Loveless, Richard Cooper, Claire Dusa, Adam Lane, Kasiani C. Myers, Akiko Shimamura, Amit S. Grover, Andrew Wehrman   +16 more
wiley   +1 more source

Case Report: Intrahepatic cholestasis: a diagnostic dilemma [version 2; peer review: 1 approved, 3 approved with reservations]

Wellcome Open Research
Cholestasis is an impairment of bile formation or bile flow. The mechanisms of cholestasis can be broadly classified into intrahepatic and extrahepatic.
Janak Koirala, Bimal Pandey, Sudeep Adhikari, Ram Chandra Panthi, Buddha Basnyat, Roshan Shrestha, Udit Acharya   +6 more
doaj   +1 more source

Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholagnitis [PDF]

, 2018
The non-invasive differentiation of malignant and benign biliary disease is a clinical challenge. Carbohydrate antigen 19-9 (CA19-9), leucine-rich α2-glycoprotein (LRG1), interleukin 6 (IL6), pyruvate kinase M2 (PKM2), cytokeratin 19 fragment (CYFRA21.1)
Blyuss, O, Cuenco, J, Dawnay, A, Kazarian, A, Manns, MP, Menon, U, Pereira, SP, Timms, JF, Wehnert, N, Whitwell, HJ   +9 more
core   +2 more sources

Success of transition to adult care in patients with pediatric‐onset chronic liver disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Previous studies on chronic pediatric‐onset conditions have highlighted the risks of loss to follow‐up, disease progression, or therapeutic nonadherence during transition. However, very few studies have focused on liver diseases.
Sarah Mongbo, Valérie Canva, Sébastien Dharancy, Guillaume Lassailly, Alexandre Louvet, Philippe Mathurin, Nassima Ramdane, Frédéric Gottrand, Madeleine Aumar   +8 more
wiley   +1 more source