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Animal Models of Middle Ear Cholesteatoma [PDF]

BioMed Research International, 2011
Middle ear acquired cholesteatoma is a pathological condition associated with otitis media, which may be associated with temporal bone resorption, otorrhea and hearing loss, and occasionally various other complications.
Koji, Takehiko, Takahashi, Haruo, Yamamoto-Fukuda, Tomomi   +2 more
core   +7 more sources

Middle Ear Glial Heterotopia Coexisting with Cholesteatoma: A Case Study [PDF]

Journal of Otology
Objective To present a rare case of glial heterotopia in the middle ear occurring in association with cholesteatoma. Patient and Intervention A 56-year-old female presented with right-sided hearing loss and otorrhea.
Ting Liu, Haijin Yi
doaj   +2 more sources

Endoscopic ear surgery in middle ear cholesteatoma

Laparoscopic, Endoscopic and Robotic Surgery, 2021
Objective: Endoscope has been used as diagnostic tool for recidivism and as an adjunct to microscopic technique in the management of cholesteatoma. At present transcanal endoscopic ear surgery (TEES) is being used as a minimally invasive alternative for ...
Satish Nair, J.G. Aishwarya, Nagamani Warrier, V Pavithra, Aditya Jain, Mehrin Shamim, Krishna Ramanathan, Pooja K. Vasu   +7 more
doaj   +2 more sources

Expression of tumor necrosis factor alpha, interleukin-1 and matrix metalloproteinase-9 and pathomorphological changes in acquired middle ear cholesteatoma [PDF]

Biomedicinska istraživanja, 2021
Introduction. The inflammatory mediators play a central role in the pathogenesis of the inflammatory process of the middle ear and cholesteatoma from the aspect of initiating and maintaining the inflammatory response to infection and lesion.
Dalibor Vranješ, Predrag Špirić, Mirjana Gnjatić   +2 more
doaj   +1 more source

Analysis of mRNA m6A modification and mRNA expression profiles in middle ear cholesteatoma

Frontiers in Genetics, 2023
Introduction: Middle ear cholesteatoma is characterized by the hyperproliferation of keratinocytes. In recent decades, N6-methyladenosine (m6A) modification has been shown to play an essential role in the pathogenesis of many proliferative diseases ...
Shumin Xie, Li Jin, Jun He, Jinfeng Fu, Tuanfang Yin, Jihao Ren, Wei Liu   +6 more
doaj   +1 more source

Microarray analysis and functional prediction of differentially expressed circular RNAs in acquired middle ear cholesteatoma

BioMedical Engineering OnLine, 2021
Background Middle ear cholesteatoma is characterized by hyper-proliferation of keratinocytes. Circular RNA (circRNA) plays an essential role in the pathogenesis of many proliferative diseases.
Shumin Xie, Li Jin, Tuanfang Yin, Jihao Ren, Wei Liu   +4 more
doaj   +1 more source

Classification and Stages of Middle Ear Cholesteatoma at the Southern Philippines Medical Center Using the European Academy of Otology and Neurotology / Japan Otological Society (EAONO / JOS) System

Philippine Journal of Otolaryngology Head and Neck Surgery, 2021
Objective: To determine the stage of middle ear cholesteatoma of patients who underwent middle ear surgery at the Southern Philippines Medical Center from January to December 2019, based on European Academy of Otology and Neurotology / Japan ...
Dominador Toral, Chris Robinson Laganao
doaj   +1 more source

Immunohistochemical localization of d‐β‐aspartic acid in congenital and acquired middle ear cholesteatoma

Laryngoscope Investigative Otolaryngology, 2022
Objective/Hypothesis Middle ear cholesteatoma is characterized by abnormal growth of the keratinizing squamous epithelium of the temporal bone. d‐β‐aspartic acid is the major isomer of d‐aspartic acid found in elderly tissue.
Shiori Kitaya, Ryoukichi Ikeda, Jun Suzuki, Hidetoshi Oshima, Yuri Nomura, Yusuke Kusano, Nobuo Ohta, Tetsuaki Kawase, Kazue Ise, Kazuhiro Murakami, Yasuhiro Nakamura, Hironobu Sasano, Yukio Katori   +12 more
doaj   +1 more source

Value of Endoscopy in Cholesteatoma Clearance: A Systematic Review [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: The primary goal of cholesteatoma surgery is to eradicate it from the middle ear cleft. However, due to linear axis of illumination of the microscope, in some of the recesses or hidden areas in middle ear are not visualised.
Prakash S Handi, Harish Onkarappa Mudhbasalar   +1 more
doaj   +1 more source

Research Progress on Non-coding RNAs in Cholesteatoma of the Middle Ear [PDF]

Clinical and Experimental Otorhinolaryngology, 2023
Cholesteatoma of the middle ear is a common disease in otolaryngology that is receiving increasing attention. It is estimated that over five million people around the world have suffered from middle ear cholesteatoma.
Dongliang Liu, Hang Zhang, Xiulan Ma, Yaodong Dong   +3 more
doaj   +1 more source