An in-depth discussion of cholesteatoma, middle ear Inflammation, and langerhans cell histiocytosis of the temporal bone, based on diagnostic results. [PDF]
Front Pediatr, 2022 Objective This study aimed to conduct an in-depth investigation of the learning framework used for deriving diagnostic results of temporal bone diseases, including cholesteatoma and Langerhans cell histiocytosis (LCH).
Duan B, Pan LL, Chen WX, Qiao ZW, Xu ZM.
europepmc +2 more sources
Pediatric Cholesteatoma Presenting as Persistent Otorrhea: A Case of Delayed Diagnosis Across Multiple ENT Specialists [PDF]
Clinical Case ReportsPediatric cholesteatoma is an aggressive but uncommon middle ear condition characterized by keratinizing squamous epithelium that can progressively erode adjacent structures.
And Elshani +10 more
doaj +2 more sources
Expression of tumor necrosis factor alpha, interleukin-1 and matrix metalloproteinase-9 and pathomorphological changes in acquired middle ear cholesteatoma [PDF]
Biomedicinska istraživanja, 2021 Introduction. The inflammatory mediators play a central role in the pathogenesis of the inflammatory process of the middle ear and cholesteatoma from the aspect of initiating and maintaining the inflammatory response to infection and lesion.
Dalibor Vranješ +2 more
doaj +1 more source
Analysis of mRNA m6A modification and mRNA expression profiles in middle ear cholesteatoma
Frontiers in Genetics, 2023 Introduction: Middle ear cholesteatoma is characterized by the hyperproliferation of keratinocytes. In recent decades, N6-methyladenosine (m6A) modification has been shown to play an essential role in the pathogenesis of many proliferative diseases ...
Shumin Xie +6 more
doaj +1 more source
BioMedical Engineering OnLine, 2021 Background Middle ear cholesteatoma is characterized by hyper-proliferation of keratinocytes. Circular RNA (circRNA) plays an essential role in the pathogenesis of many proliferative diseases.
Shumin Xie +4 more
doaj +1 more source
Philippine Journal of Otolaryngology Head and Neck Surgery, 2021 Objective: To determine the stage of middle ear cholesteatoma of patients who underwent middle ear surgery at the Southern Philippines Medical Center from January to December 2019, based on European Academy of Otology and Neurotology / Japan ...
Dominador Toral, Chris Robinson Laganao
doaj +1 more source
Review of potential medical treatments for middle ear cholesteatoma
Cell Communication and Signaling, 2022 Middle ear cholesteatoma (MEC), is a destructive, and locally invasive lesion in the middle ear driven by inflammation with an annual incidence of 10 per 100,000.
M. Schürmann, P. Goon, H. Sudhoff
semanticscholar +1 more source
Laryngoscope Investigative Otolaryngology, 2022 Objective/Hypothesis Middle ear cholesteatoma is characterized by abnormal growth of the keratinizing squamous epithelium of the temporal bone. d‐β‐aspartic acid is the major isomer of d‐aspartic acid found in elderly tissue.
Shiori Kitaya +12 more
doaj +1 more source
Research Progress on Non-coding RNAs in Cholesteatoma of the Middle Ear [PDF]
Clinical and Experimental Otorhinolaryngology, 2023 Cholesteatoma of the middle ear is a common disease in otolaryngology that is receiving increasing attention. It is estimated that over five million people around the world have suffered from middle ear cholesteatoma.
Dongliang Liu +3 more
doaj +1 more source
The significance of the expression of cell proliferation and inflammation markers in the development of acquired middle ear cholesteatoma [PDF]
Vojnosanitetski Pregled, 2018 Background/Aim. Permanent proliferation and periodical infection are the main clinical characteristics of acquired middle ear cholesteatoma. The aim of this study was to research immunohistochemical characteristics of the skin along with the ...
Erdoglija Milan +5 more
doaj +1 more source