Results 151 to 160 of about 55,634 (225)

Chronic rhinosinusitis could increase the risk of cholesteatoma of middle ear

International Forum of Allergy and Rhinology, 2022
BACKGROUND Chronic rhinosinusitis (CRS) is an inflammatory disease of the sinonasal mucosa. Inflammation of the sinonasal mucosa often can cause obstruction of the eustachian tube, with subsequent impairment of pressure regulation in the middle ear ...
Dae-Soon Son, Minseob Cho, Dong-Kyu Kim
semanticscholar   +1 more source

Expression of PTHrP and RANKL in acquired middle ear cholesteatoma epithelium

Acta Oto-Laryngologica, 2020
Background: Regarded as the most important clinical characteristic of middle ear cholesteatoma, the exact mechanism of bone resorption in cholesteatoma still remains unknown.
S. Xie, Zhen Pan, T. Yin, Jihao Ren, Wei Liu   +4 more
semanticscholar   +1 more source

Occult Cholesteatoma of the Middle Ear

ORL, 1978
A clinico-pathological study of 10 cases (including histopathology) indicates that occult cholesteatoma is neither a congenital cholesteatoma nor an epidermoid cyst, originating in the attic through a melaplastic process of middle ear mucosa behind an intact tympanic membrane.
M. Redli, C.R. Pfaltz
openaire   +3 more sources

Autophagy Is Deficient and May be Negatively Regulated by SERPINB3 in Middle Ear Cholesteatoma.

Otology and Neurotology, 2020
HYPOTHESIS Whereas autophagy has been linked to various human diseases, whether it also plays a role in cholesteatoma is virtually unknown. This study aimed to investigate the activity and regulation of autophagy in cholesteatoma.
K. Ho, Chih-Jen Huang, C. Hung, Yu-Rong Wu, C. Chiu, Chen-Yu Chien, Hsun‐Mo Wang, N. Chang, I.-Ling Lin, Jeff Yi‐Fu Chen   +9 more
semanticscholar   +1 more source

Keratinocyte growth factor signaling promotes stem/progenitor cell proliferation under p63 expression during middle ear cholesteatoma formation.

Current Opinion in Otolaryngology & Head and Neck Surgery, 2020
PURPOSE OF REVIEW Middle ear cholesteatoma is an epithelial lesion that expands into the middle ear, resulting in bone destruction. However, the pathogenesis of this has been unknown.
Tomomi Yamamoto-Fukuda, Naotaro Akiyama
semanticscholar   +1 more source

Congenital Middle Ear Cholesteatoma

Archives of Pediatrics & Adolescent Medicine, 1983
A congenital aural cholesteatoma is a cystic epithelial remnant of embryonal origin found medial to the intact tympanic membrane. This entity may be identified in young children who have not had perforated eardrums and who have had no history of otitis media.
Bruce Feldman, William J. McAVENEY, Kenneth M. Grundfast, Marco A. Merida, Richard H. Schwartz   +4 more
openaire   +3 more sources

MRI of a middle ear cholesteatoma in a cat

Veterinary Radiology & Ultrasound, 2022
AbstractA 9‐year‐old Maine coon cat presented with right‐sided Horner and facial nerve paralysis. Magnetic resonance imaging (MRI) showed a heterogeneously contrast‐enhancing mass occupying the right dorsolateral compartment of the tympanic cavity and extending into the ventromedial compartment, which was expanded and fluid filled.
Arielle, Herberger, James, Hammond, Andrew, Miller, Benjamin, Olson   +3 more
openaire   +2 more sources

Integrin Expression In Middle Ear Cholesteatoma

Acta Oto-Laryngologica, 1994
Cholesteatoma is lined by a squamous keratinizing epithelium exhibiting most of the features of normal epidermis. In this study, we investigated by immunohistochemistry the expression of integrin adhesion molecules in primary acquired and recurrent cholesteatomas, and compared it with common epidermal cysts and normal human skin.
Dallari S, Cavani A, Bergamini G, GIROLOMONI, Giampiero   +3 more
openaire   +4 more sources

Lymphotoxin in Human Middle Ear Cholesteatoma

The Laryngoscope, 1991
The progressive growth of epidermis appears to be a crucial factor in the pathogenesis of cholesteatoma. How this growth is encouraged is still not well understood. In the present study, lymphotoxin was found in human middle ear cholesteatoma tissues by the immunoperoxidase method using rabbit anti‐human lymphotoxin immunoglobulin G (IgG).
Cheng-Chun Huang, Shi-Du Yan
openaire   +3 more sources

Middle ear cholesteatoma: An animal model

American Journal of Otolaryngology, 1985
Topical otic preparations now in clinical use contain a variety of antibiotics and solvents that may produce severe inflammation if they reach the middle ear cavity. This report describes the response of the chinchilla middle ear to direct application of one such preparation that appears to act as a nonspecific irritant.
Dennis K. Burns, Charles G. Wright, William L. Meyerchoff   +2 more
openaire   +3 more sources