Results 211 to 220 of about 1,523,799 (296)

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

Role of Oxysterol-Binding Protein Family in Cholesterol Metabolism and Cancer Progression: A Review. [PDF]

Med Sci Monit
Wu Y, Lv X, Yang J, Liu S, Chen Y, Yuan Z, Wang X.   +6 more
europepmc   +1 more source

Refinement of a Published Gene‐Physical Activity Interaction Impacting HDL‐Cholesterol: Role of Sex and Lipoprotein Subfractions [PDF]

Kenneth E. Westerman, Tuomas O. Kilpeläinen, Magdalena Sevilla-González, Margery A. Connelly, Alexis C. Wood, Michael Y. Tsai, Kent D. Taylor, Stephen S. Rich, Jerome I. Rotter, James D. Otvos, Amy R. Bentley, Samia Mora, Hugues Aschard, D. C. Rao, C. Charles Gu, Daniel I. Chasman, Alisa K. Manning, The CHARGE Gene‐Lifestyle Interactions Working Group   +17 more
openalex   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Association Between High-Density Lipoprotein Characteristics and Hemostatic Parameters in the Netherlands Epidemiology of Obesity (NEO) Study-Brief Report. [PDF]

Arterioscler Thromb Vasc Biol
Yuan L, Han J, Cheng S, Rosendaal FR, Mook-Kanamori DO, Jukema JW, Vink H, van den Berg BM, Rabelink TJ, van Hylckama Vlieg A, Tietge UJF, Willems van Dijk K, Li-Gao R.   +12 more
europepmc   +1 more source

177 Effect of dietary feed additives in laying chicken on egg production, nutrient content, yolk cholesterol, and egg quality traits [PDF]

Md Sazedul Karim Sarker, Farhana Sharmin, Jannatara Khatun, Nasrin Sultana, S Faruque, Umme Saleheen Ety, Nushrat Nourin Lisa, A. B. M. Alim Al Islam   +7 more
openalex   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Antisense oligonucleotide targeting TARDBP-EGFR splicing axis inhibits progression of oral squamous cell carcinoma through ABCA1-regulated cholesterol efflux. [PDF]

Int J Oral Sci
Ni N, Wang M, Yuan Z, Zhang L, Cai J, Du Q, Li P, Gao C, Zhang H, Li Y, Yuan H.   +10 more
europepmc   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

A-241 Effect of remnant cholesterol to low density lipoprotein cholesterol (LDL-C) ratio on the accuracy of direct LDL-C measurement [PDF]

Sang‐Guk Lee, Soon Sung Kwon, Chan-Ik Cho   +2 more
openalex   +1 more source