Results 161 to 170 of about 14,466 (210)

Oxysterol signaling in the central nervous system: cellular mechanisms and implications for neurodegeneration. [PDF]

Front Mol Neurosci
Ricci RP, Foo CX, Ronacher K, Cullen CL.
europepmc   +1 more source

Regulatory roles of bioactive lipids in vascular homeostasis and remodeling. [PDF]

Med Rev (2021)
Yang J, Xiao H, Zhang Z, Zhang L, Zhang X.   +4 more
europepmc   +1 more source

Development of semi-dwarf Echinacea purpurea by inducing silencing of the endogenous brassinosteroid-biosynthetic gene DWF4. [PDF]

BMC Plant Biol
Zhao J, Liu J, He Y, Fu Y.
europepmc   +1 more source

Protein kinase C epsilon deletion in AgRP neurons modulates hypothalamic glucose sensing and improves glucose tolerance in mice. [PDF]

Mol Metab
Brandon AE, Yan C, Zhang X, Ip CK, Gao Z, Lee NJ, Marian OC, Perez A, Don AS, Herzog H, Small L, Shi YC, Schmitz-Peiffer C.   +12 more
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Deletion of CH25H and LIPA Genes in Human Abolishes Biosynthesis of 25-Hydroxycholesterol but not of 7α,25-Dihydroxysterols and Enhances Non-enzymatic Cholesterol Oxidation: Metabolic Changes are Partially Reversed by Hematopoietic Stem Cell Transplant^‡

Yutuc E, Ghosh A, Abdel-Khalik J, Goenka A, Asgari MA, Lopez-Castejon G, Beaman GM, Wynn RF, Newman WG, Jones SA, Griffiths WJ, Wang Y.   +11 more
europepmc   +1 more source

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Structure of the rat gene encoding cholesterol 7.alpha.-hydroxylase

Biochemistry, 1990
Cholesterol 7 alpha-hydroxylase (7 alpha-hydroxylase) is a microsomal cytochrome P-450 that catalyzes the first and rate-limiting step in bile acid biosynthesis, the major catabolic pathway in cholesterol homeostasis. The gene encoding the rat 7 alpha-hydroxylase has been isolated and characterized.
D F, Jelinek, D W, Russell
openaire   +2 more sources

Transcriptional regulation of the human cholesterol 7.alpha.-hydroxylase gene

Biochemistry, 1992
As an initial step toward understanding the transcriptional regulation of cholesterol 7 alpha-hydroxylase (CYP7) in man, we isolated and functionally characterized the 5'-flanking region of the human CYP7 gene. The nucleotide sequences of the first exon and 1.6 kb preceding the exon were determined and found to contain a TATA box at position -30, a ...
D T, Molowa, W S, Chen, G M, Cimis, C P, Tan   +3 more
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Increased bile acid pool inhibits cholesterol 7 alpha-hydroxylase in cholesterol-fed rabbits

Gastroenterology, 1997
Cholesterol feeding unexpectedly inhibits cholesterol 7 alpha-hydroxylase in rabbits. The aim of this study was to explore the mechanism.Twenty male New Zealand white rabbits were fed regular chow with and without 2% cholesterol for 10 days followed by 7 days of bile drainage.
G, Xu, G, Salen, S, Shefer, G S, Tint, B T, Kren, L B, Nguyen, C J, Steer, T S, Chen, L, Salen, D, Greenblatt   +9 more
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