Results 171 to 180 of about 14,466 (210)

Polymorphisms of human cholesterol 7α-hydroxylase

Biochemical and Biophysical Research Communications, 1992
Human liver cholesterol 7 alpha-hydroxylase (CYP7) cDNAs were isolated from a human liver cDNA library. A full-length cDNA has 2901 nucleotides which encode a typical P450 polypeptide of 504 amino acid residues. Two different sequences of codon 100, TTT (Phe) and TCT (Ser), were identified in cDNA clones.
W G, Karam, J Y, Chiang
openaire   +2 more sources

[Cholesterol-7-alpha-hydroxylase activity in cholelithiasis].

Minerva medica, 1977
The physiopathological mechanism of cholesterol supersaturation in the bile was investigated by determining cholesterol-7-alpha-hydroxylase activity in 5 normal controls and 8 subjects with cholesterol gallstones. Bile lipids were also evaluated. Hydroxylase values were higher (though not significantly) in the controls. A linear correlation (r = 0.797)
N, Carulli, F B, Ubertino, F, Bosco Ubertino, M, Ponz de Leon, S, Calandra   +4 more
openaire   +1 more source

Cholesterol-7α-hydroxylase of pigeon liver microsomes

Archives of Biochemistry and Biophysics, 1974
Abstract The assay conditions and properties of pigeon liver cholesterol-7α-hydroxylase were studied to provide a basis for comparison of the enzyme activity in pigeon strains. The specific activity of 7α-tritium in [7α, 7β-3H]cholesterol was obtained by determining the ratio of tritiated water to 7α-hydroxy [7β-3H]cholesterol following catalysis by ...
F H, Hulcher, W H, Oleson, H B, Lofland
openaire   +2 more sources

Regulation of cholesterol 7 alpha-hydroxylase by different effectors.

The Italian journal of gastroenterology, 1997
Cholesterol degradation to bile acids represents 50% of total elimination of cholesterol from the body each day. Cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase catalyze initial steps in the neutral and acidic pathways, respectively. Both enzymes were recently cloned and sequenced, and hence the molecular basis of their regulation could be ...
openaire   +1 more source

Effects of 3-methylcholanthrene and DDT on cholesterol 7 alpha-hydroxylase in rats.

Drug-nutrient interactions, 1984
The possibility that cholesterol 7 alpha-hydroxylase activity and cholesterol metabolism could be mediated by chemical inducers of the microsomal mixed function oxidase (MFO) system was investigated. Groups of male Wistar rats weighing about 250 gm were treated with the inducer compounds, DDT, phenobarbital, or 3-methylcholanthrene, or with the ...
B S, Appleton, C N, Shriver, L, Arnrich, J N, Hathcock   +3 more
openaire   +1 more source

Effect of Covid-19 Vaccination on Transmission of Alpha and Delta Variants

New England Journal of Medicine, 2022
David W Eyre, Mark Purver, Koen B Pouwels   +2 more
exaly  

Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes

Cell, 2021
Hannah Scheiblich, Susanne V Schmidt, Luc Bousset   +2 more
exaly  

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice

Cell Metabolism, 2020
Azar Asadi Shahmirzadi
exaly  

[Cholesterol 7 alpha-hydroxylase].

Nihon rinsho. Japanese journal of clinical medicine, 2001
M, Kai, M, Yamada, J, Nagatomo, T, Setoguchi   +3 more
openaire   +1 more source

[Determination of cholesterol-7 alpha-hydroxylase].

Archives internationales de physiologie et de biochimie, 1969
J, Van Cantfort, J, Gielen, J, Renson
openaire   +1 more source