Biophysical Modelling of Antimicrobial Peptide’s Interactions with Phospholipid and Lipopolysaccharide Membranes [PDF]
Antimicrobial peptides (AMPs) are naturally-occurring peptide antibiotics. The way they work has inspired a vigorous search for optimized peptide antibiotics for fighting resistant bacteria. Cationic AMPs cleverly utilize their electrostatic interactions
Nourbakhsh, Shokoofeh
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EFFECT OF FLUORINATION ON PARTITIONING BEHAVIOR AND BILAYER SELF ASSEMBLY [PDF]
Fluorinated systems are defined by unique properties that offer advantages in drug delivery, material synthesis and industrial applications. In comparison to their hydrocarbon counterparts, the design of fluorinated solutes for tailored applications is ...
Ojogun, Vivian Aramide
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Using Allosteric Transition Models to Gain Insight on the Signaling Response of Membrane Modulated Proteins [PDF]
University of Minnesota M.S. thesis. July 2016. Major: Chemistry. Advisor: Anne Hinderliter. 1 computer file (PDF); x, 106 pages.The signaling response of membrane modulated proteins are influenced by their complex lipid environments.
Kobany, Stephanie
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Lipid bilayer phase separations, cholesterol, and their effect on the amyloid precursor protein C99 [PDF]
The Amyloid Cascade hypothesis provides a molecular-level mechanism for the etiology of Alzheimer’s Disease (AD) and proposes a central role for the genesis and aggregation of Aβ protein.
Pantelopulos, George A.
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Structural effects of neutral lipids on the divalent cation-induced interactions of phosphatidylserine - containing bilayers [PDF]
As Ca2+ and phosphatidylserine (PS) are known to induce the adhesion of bilayer vesicles and form collapsed multibilayer structures in vitro, it was the aim of this study to examine how that interaction and the resultant structures might be modified by
Coorssen, Jens R.
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Investigating spatial distribution and dynamics of membrane proteins in polymer-tethered lipid bilayer systems using single molecule-sensitive imaging techniques [PDF]
Indiana University-Purdue University Indianapolis (IUPUI)Plasma membranes are complex supramolecular assemblies comprised of lipids and membrane proteins. Both types of membrane constituents are organized in highly dynamic patches with profound impact on
Ge, Yifan
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Mechanisms Of Membrane Remodeling By Bar Proteins [PDF]
Numerous physiological phenomena involve highly curved cell membranes with significant shape diversity. The diversity of cell membrane shape is partly regulated by a large family of BAR proteins, which consists of several different classes, including ...
Chen, Zhiming
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Scale up of Transmembrane NADH Oxidation in Synthetic Giant Vesicles. [PDF]
Wang M +8 more
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Investigating Liquid-Liquid Phase Separation in Lipid Bilayers: A Multi-Modal Approach Utilizing Spectroscopy, Microscopy, and Cryo-EM [PDF]
This thesis explores the characterization of liquid-liquid phase separation in model lipid bilayers using fluorescence, optical microscopy, and cryo-electron microscopy (cryo-EM) integrated with machine learning (ML) analysis.
Sharma, Karan D
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Non-linear solitary sound waves in lipid membranes and their possible role in biological signaling. [PDF]
Thesis (Ph. D.)--Boston UniversityBiological macromolecules self-assemble under entropic forces to form a dynamic 20 interfacial medium where the elastic properties arise from the curvature of the entropic potential of the interface.
Shrivastava, Shamit
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