Results 91 to 100 of about 23,102 (293)

The effect of oligomeric procyanidins on endothelial function and cholesterol homeostasis

, 2012
PhDOligomeric procyanidins (OPC) are naturally occurring dietary substances, which studies suggest can protect against cardiovascular disease. To explore this further a double-blind randomised controlled crossover trial, EPICURE (Evaluation of high ...
Rull, Gurvinder Kaur
core  

Role of Lp A-I and Lp A-I/A-II in Cholesteryl Ester Transfer Protein–Mediated Neutral Lipid Transfer

, 1996
The two major subclasses of HDL contain apo A-I only (Lp A-I) or both apo A-I and apo A-II (Lp A-I/A-II). We have carried out experiments to quantify the participation of Lp A-I and Lp A-I/A-II in the neutral lipid transfer reaction in normal and ...
Alan D. Edgar, Ruth McPherson, Yves L. Marcel, Geneviève Agnani, Jean-Charles Fruchart, Paulina Lau   +5 more
core   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

A Role of the Bile Salt Receptor FXR in Atherosclerosis

, 2010
This study reviews current insights into the role of bile salts and bile salt receptors on the progression and regression of atherosclerosis. Bile salts have emerged as important modifiers of lipid and energy metabolism.
Albert K. Groen, Hageman, Jurre, Herrema, H.J., Folkert Kuipers, Hageman, J., Kuipers, Folkert, Herrema, Hilde, Hilde Herrema, Kuipers, Folkert; id_orcid, Groen, A.K., Kuipers, F., Groen, Albert K., Jurre Hageman   +12 more
core   +1 more source

APOE-knockout in rabbits causes loss of cells in nucleus pulposus and enhances the levels of inflammatory catabolic cytokines damaging the intervertebral disc matrix.

PLoS ONE, 2019
Rabbits with naturally high levels of cholesterol ester transfer protein (CETP), unlike rodents, have become an interesting animal model for the study of lipid metabolism and atherosclerosis, as they have similarities to humans in lipid metabolism ...
Anja Beierfuß, Monika Hunjadi, Andreas Ritsch, Christian Kremser, Claudius Thomé, Demissew Shenegelegn Mern   +5 more
doaj   +1 more source

Plasma cholesteryl ester transfer protein mass and phospholipid transfer protein activity are associated with leptin in type 2 diabetes mellitus

, 2007
Adipose tissue contributes to plasma levels of lipid transfer proteins and is also the major source of plasma adipokines. We hypothesized that plasma cholesteryl ester transfer protein (CETP) mass, phospholipid transfer protein (PLTP) activity and ...
Dullaart, R. P. F., Tol, Aad, Sluiter, W. J., Dullaart, RPF, Dallinga-Thie, GM, Dallinga-Thie, G. M., Sluiter, Wim, de Vries, R., R.P.F. Dullaart, van Tol, A., R. de Vries, W.J. Sluiter, G.M. Dallinga-Thie, A. van Tol, Vries, R.   +14 more
core   +1 more source

The Effects of Enzyme Pretreatment Extraction on Lipid Recovery With Normal Phase HPLC

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT With the increasing interest in the commercialization of microalgal fermentation‐based products, sustainable and efficient oil extraction methods have been developed for manufacturing and analytical testing. Due to the variability and resilience of micro‐algae cell walls, traditional lipid extraction methods such as Folch and Bligh and Dyer ...
Zhehan Jiang, Luke MacPherson, Suzanne M. Budge, Wei Xia, Roberto E. Armenta   +4 more
wiley   +1 more source

Recent Advances in Membrane Microdomains: Rafts, Caveolae, and Intracellular Cholesterol Trafficking

, 2001
Cellular cholesterol homeostasis is a balance of influx, catabolism and synthesis, and efflux. Unlike vascular lipoprotein cholesterol transport, intracellular cholesterol trafficking is only beginning to be resolved.
Adalberto M. Gallegos, Huan Huang, Barbara P. Atshaves, Hsu Chao, Olga Starodub, Andrey Frolov, Stephen M. Storey, Friedhelm Schroeder, Huiqin Yang, Ann B. Kier, Avery L. Mcintosh, Anca D. Petrescu   +11 more
core   +1 more source

Stabilization of PUFA‐Rich Mayonnaise Against Lipid Oxidation: A Review of the Last Three Decades of Research

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Mayonnaise, a widely consumed oil‐in‐water emulsion, is highly susceptible to lipid oxidation due to its high content of polyunsaturated fatty acids (PUFAs) and the presence of pro‐oxidant factors such as low pH and iron from egg yolk. Over the past three decades, extensive research has focused on understanding oxidation mechanisms, analytical
Sakhi Ghelichi, Betül Yesiltas, Charlotte Jacobsen   +2 more
wiley   +1 more source

High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants.

, 2008
Cholesteryl ester transfer protein (CETP) and hepatic lipase (HL) are two HDL modifying proteins that have both pro- and anti-atherogenic properties. We hypothesized that CETP and HL synergistically affect HDL cholesterol and atherosclerotic risk.
Jukema, J.W., Boer, J.M., Sijbrands, E.J.G.; id_orcid, Kuivenhoven, J.A., Seidell, Jacob C, Botma, Gert-Jan, Acker, BAC, Zwinderman, Aeilko H, Kastelein, JJP, Jansen, H., Acker, B.A. van, Sijbrands, E.J.G., Verhoeven, Adrie, Jukema, J Wouter, van Acker, B.A., Kuivenhoven, Jan Albert, Kuivenhoven, JA, Jansen, Hans, Dallinga-Thie, Geesje M, Zwinderman, A.H., Boer, Jolanda M A, Botma, GJ (Gerrit Jan), Dallinga-Thie, GM, Seidell, JC, Jansen, H, Verhoeven, A.J., Sijbrands, E.J., Dallinga-Thie, G.M., Kastelein, J.J., Sijbrands, Eric J G, Jansen, H., Zwinderman, AH, Verhoeven, Adrie J M, Boer, JMA, Seidell, J.C., van Acker, Bernadette A C, Jukema, JW, Botma, G.J., Kastelein, John J P, Seidell, Jacob C; id_orcid   +39 more
core   +1 more source