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As a model for the formation of beta-very low density lipoproteins (VLDL) and small, dense LDL by the intraplasma metabolic activities in vivo, lipoproteins in fresh plasma were interacted in vitro with endogenous lecithin:cholesterol acyltransferase (LCAT) and cholesterylester transfer proteins (CETP) and subsequently with purified lipoprotein lipase (
Jere P. Segrest+2 more
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Treatment of diabetic dyslipoproteinemia.
Experimental and clinical endocrinology & diabetes, 2003Diabetes mellitus, specifically type 2, is often associated with disorders in lipid metabolism. Elevated levels of plasma free fatty acids play a pivotal role by contributing significantly to insulin resistance.
A. Steinmetz
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Arteriosclerosis, Thrombosis and Vascular Biology, 2019
Background: Impaired reverse cholesterol transport is associated with increased atherosclerosis. Cholesterol efflux from macrophages (CEC) is the initial step of reverse cholesterol transport and is inversely associated with cardiovascular disease ...
M. Metzinger+4 more
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Background: Impaired reverse cholesterol transport is associated with increased atherosclerosis. Cholesterol efflux from macrophages (CEC) is the initial step of reverse cholesterol transport and is inversely associated with cardiovascular disease ...
M. Metzinger+4 more
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Future of cholesteryl ester transfer protein inhibitors.
Annual Review of Medicine, 2014The cholesteryl ester transfer protein (CETP) plays an integral role in the metabolism of plasma lipoproteins. Despite two failures, CETP inhibitors are still in clinical development.
D. Rader, Emil M Degoma
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European Journal of Clinical Investigation, 1987
R. Dullaart, J. Groener, D. Erkelens
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R. Dullaart, J. Groener, D. Erkelens
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Novel lipid modifying drugs to lower LDL cholesterol
Current Opinion in Lipidology, 2017A. Cupido, L. Reeskamp, J. Kastelein
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A Comprehensive Survey on Transfer Learning
Proceedings of the IEEE, 2021Dongbo Xi, Fuzhen Zhuang, Zhiyuan Qi
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