Results 291 to 300 of about 77,038 (354)

Group A Streptococcus interacts with glycosaminoglycans via M proteins to modulate bacterial adherence in vitro

The FEBS Journal, Volume 292, Issue 20, Page 5540-5562, October 2025.
Interactions between bacteria and the extracellular matrix are a prerequisite for colonisation and infection. Phylogenetically diverse M proteins of group A Streptococcus (GAS) can selectively bind sulfated glycosaminoglycans with high affinity. M protein‐mediated recruitment of chondroitin sulfate and dermatan sulfate was shown to increase GAS ...
Tahnee B.‐D. McEwan, David M. P. De Oliveira, Emily K. Stares, Lauren E. Hartley‐Tassell, Christopher J. Day, Mark J. Walker, Michael P. Jennings, Ronald Sluyter, Martina L. Sanderson‐Smith   +8 more
wiley   +1 more source

Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate. [PDF]

Nat Commun
Vidal-Calvo EE, Martin-Salazar A, Choudhary S, Dagil R, Raghavan SSR, Duvnjak L, Nordmaj MA, Clausen TM, Skafte A, Oberkofler J, Wang K, Agerbæk MØ, Løppke C, Jørgensen AM, Ropac D, Mujollari J, Willis S, Garcias López A, Miller RL, Karlsson RTG, Goerdeler F, Chen YH, Colaço AR, Wang Y, Lavstsen T, Martowicz A, Nelepcu I, Marzban M, Oo HZ, Ørum-Madsen MS, Wang Y, Nielsen MA, Clausen H, Wierer M, Wolf D, Gögenur I, Theander TG, Al-Nakouzi N, Gustavsson T, Daugaard M, Salanti A.   +40 more
europepmc   +1 more source

Expression of Heart Development Protein With EGF‐Like Domains 1 (HEG1) Decorated With Low‐Sulfated Keratan Sulfate in Human Malignant Pleural Mesothelioma

Pathology International, Volume 75, Issue 10, Page 504-512, October 2025.
The purpose of this study is to investigate sulfation modification of the glycan structure decorating HEG1, one of the diagnostic markers of malignant pleural mesothelioma (MPM), in MPM. Immunohistochemical analysis reveals low‐sulfated keratan sulfate (KS) expression, recognized by 294‐1B1 and R‐10G, in MPM tissues with HEG1 expression.
Koki Nakashima, Hitomi Hoshino, Zui Zhang, Tomoya O. Akama, Nobuyuki Kondo, Seiki Hasegawa, Yoshitaka Sekido, Mana Fukushima, Tamotsu Ishizuka, Motohiro Kobayashi   +9 more
wiley   +1 more source

Delivery of Nitric Oxide by Chondroitin Sulfate C Increases the Rate of Wound Healing through Immune Modulation. [PDF]

ACS Appl Bio Mater
Picciotti SL, El-Ahmad H, Bucci MP, Grayton QE, Wallet SM, Schoenfisch MH.   +5 more
europepmc   +1 more source

Chondroitin sulfate nanoparticles based on co-delivery dual drug induced ferroptosis in lung cancer cells by disrupting mitochondrial oxidative homeostasis. [PDF]

Mater Today Bio
Wang H, Lin S, Xie J, Chen X, Deng Y, Huang P, Peng K, Gao W, Ye G, Wang G, Yu X, Wen H, Qin L, Zhou Y.   +13 more
europepmc   +1 more source

Can Hyaluronic Acid Combined with Chondroitin Sulfate in Viscosupplementation of Knee Osteoarthritis Improve Pain Symptoms and Mobility? [PDF]

Biomolecules
Dima A, Dragosloveanu M, Romila AR, Cristea A, Marinică G, Dănilă AT, Mandici A, Cojocariu D, Vlad RA, Ciurba A, Bîrsan M.   +10 more
europepmc   +1 more source

Chondroitin Sulfate Ameliorates Hypertension in Male Offspring Rat Born to Mothers Fed an Adenine Diet. [PDF]

Antioxidants (Basel)
Tain YL, Hou CY, Chang-Chien GP, Lin SF, Hsu CN.   +4 more
europepmc   +1 more source

Dual-drug loaded chondroitin sulfate embolization beads enhance TACE therapy for HCC by integrating embolization, chemotherapy, and anti-angiogenesis. [PDF]

Mater Today Bio
Huang JX, Yang R, Long H, Kong J, Shao GQ, Xiong F.   +5 more
europepmc   +1 more source

Targeting chondroitin sulfate suppresses macropinocytosis of breast cancer cells by modulating syndecan-1 expression. [PDF]

Mol Oncol
Yen HR, Liao WC, Chen CH, Su YA, Huang YW, Hsiao C, Chou YL, Chu YH, Shih PK, Liu CH.   +9 more
europepmc   +1 more source

Biosynthesis of animal-free recombinant chondroitin sulfate E using a functional chondroitin sulfotransferase in E. coli. [PDF]

Appl Microbiol Biotechnol
Tithi AD, Song Y, Paskaleva E, Koffas M.
europepmc   +1 more source