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Isolation and Purification of Chondroitin Sulfate
2006Publisher Summary This chapter discusses methods for the isolation and purification of chondroitin sulfate (CS). This molecule is a sulfated glycosaminoglycan (GAG) composed of a linear polysaccharide chain with repeating disaccharides of defined structures that usually contain one hexosamine, one hexuronic acid, and a sulfate ester.
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In Vitro Effects of Chondroitin Sulfate
2006Publisher Summary A number of in vitro studies have been performed to determine the mode of action of chondroitin sulfate (CS). It has been demonstrated that CS possesses both anabolic effects on cartilage metabolism and anticatabolic properties. In various models of cartilage culture or of isolated chondrocytes, CS has demonstrated the capacity to ...
A. Fioravanti, G. Collodel
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Chondroitin Sulfate and RBC Clumping
Archives of Ophthalmology, 1984To the Editor. —Chondroitin sulfate is a new viscoelastic substance that is advocated as a protective agent for intraocular lens insertion. Chondroitin sulfate has been shown to be more effective in protecting the endothelium of animal and human corneas than other substances.1Contact of intraocular lenses with endothelium causes endothelial damage and
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Immunology of Chondroitin/Dermatan Sulfate
1995Variable substitutions and locations of the sulfate esters along the backbone of chondroitin/dermatan sulfate chains, combined with their carbohydrate structures, present topographies to immune systems which can be recognized as antigenic. This has led to the development of a number of monoclonal antibodies which recognize distinct epitopes in the ...
Ronald J. Midura +3 more
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Chondroitin sulfate for knee osteoarthritis
Annals of the Rheumatic Diseases, 2018The apparent efficacy of chondroitin sulfate in treating knee osteoarthritis reported by Reginster et al 1 must be considered in the context of the literature on this subject. The results of trials of chondroitin and/or glucosamine for relief of pain caused by osteoarthritis of the knee and hip have been …
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[34] Microsomal sulfation of proteochondroitin, chondroitin, and chondroitin oligosaccharides
1989Publisher Summary This chapter focuses on the microsomal sulfation of proteochondroitin, chondroitin, and chondroitin oligosaccharides. Chondroitin sulfate—a polymer of gIucuronic acid (GlcA) and N-acetyl galactosamine (GalNAc)—can be sulfated on either or both the 4 and 6 positions of the GalNAc and on the 2 position of the GlcA. Chondroitin sulfate
Donald E. Humphries +2 more
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Degradation of Chondroitin Sulfate and Dermatan Sulfate with Chondroitin Lyases
2003Robert J. Linhardt, María J. Hernáiz
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