Results 251 to 260 of about 54,015 (281)
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Biosynthesis of chondroitin sulfate: Microsomal proteoglycans
Biochemical and Biophysical Research Communications, 1978Abstract A microsomal preparation from chick embryo epiphyseal cartilage was incubated with UDP-[ 14 C]glucuronic acid and UDP-N-acetylgalactosamine to form [ 14 C] chondroitin-labeled proteoglycan. Two [ 14 C]proteoglycan populations were obtained which differed in size, [ 14 C]glycosaminoglycan content, and susceptibility to alkali.
Jeremiah E. Silbert +3 more
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Chondroitin Sulfate Proteoglycans in the Brain
2006Publisher Summary Chondroitin sulfate proteoglycans (CSPGs) play important roles in the morphogenesis and maintenance of various tissues, including the central nervous system (CNS), through the interactions of their core proteins and/or chondroitin sulfate (CS) chains with cell adhesion molecules, extracellular matrix (ECM) molecules, and growth ...
Sachiko Aono, Atsuhiko Oohira
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Chondroitin Sulfate Proteoglycans in Tumor Progression
2006Publisher Summary This chapter discusses the implication of stromal and cell surface chondroitin sulfate proteoglycans (CSPGs) to the different aspects of tumor growth and metastasis. In a developing tumor, several CSPGs are overexpressed and deposited into extracellular matrix (ECM) during the stromal reaction. The accumulated PGs participate in the
Wegrowski, Y., F.X., Maquart
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Biosynthetic Precursors of Cartilage Chondroitin Sulfate Proteoglycan
Collagen and Related Research, 1987Early steps in the biosynthesis of chondroitin sulfate proteoglycan (CSPG) and collagenous cartilage matrix molecules were examined by the comparison of products translated in mRNA-directed cell-free reactions and those synthesized by intact cartilage cells.
Barbara M. Vertel, Youssef Hitti
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Journal of Periodontal Research, 1989
This study investigated the immunohistochemical localization of chondroitin sulfate (chondroitin, 4-sulfate and 6-sulfate) and dermatan sulfate proteoglycan (PG) in human gingival connective tissue, using monoclonal antibodies. Dermatan sulfate was found
T. Shibutani, Y. Murahashi, Y. Iwayama
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This study investigated the immunohistochemical localization of chondroitin sulfate (chondroitin, 4-sulfate and 6-sulfate) and dermatan sulfate proteoglycan (PG) in human gingival connective tissue, using monoclonal antibodies. Dermatan sulfate was found
T. Shibutani, Y. Murahashi, Y. Iwayama
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The inhibitory effects of chondroitin sulfate proteoglycans on oligodendrocytes
Journal of Neurochemistry, 2011J. Neurochem. (2011) 119, 176–188.AbstractThe formation of the glial scar following a spinal cord injury presents a significant barrier to the regenerative process. It is primarily composed of chondroitin sulfate proteoglycans (CSPGs) that can inhibit axonal sprouting and regeneration.
Donna J. Osterhout, Justin R. Siebert
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Deglycosylation of chondroitin sulfate proteoglycan and derived peptides
Biochemistry, 1990In order to define the domain structure of proteoglycans as well as identify primary amino acid sequences specific for attachment of the various carbohydrate substituents, reliable techniques for deglycosylating proteoglycans are required. In this study, deglycosylation of cartilage chondroitin sulfate proteoglycan (CSPG) with minimal core protein ...
Richard C. Krueger +2 more
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Hydraulic conductivity of chondroitin sulfate proteoglycan solutions
Archives of Biochemistry and Biophysics, 1989The hydraulic conductivity of solutions of Swarm rat chondrosarcoma proteoglycan subunit and of chondroitin 4- and 6-sulfate up to concentrations of 80 mg ml-1 have been measured under physiological conditions using sedimentation velocity and membrane ultrafiltration techniques.
Wayne D. Comper, Oliver Zamparo
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Journal of Leukocyte Biology, 1992
Abstract Proteoglycan production was examined in cultures of thioglycollate-elicited peritoneal macrophages obtained from White Carneau and Show Racer pigeons. Following a 24-h incubation in the presence of [35S]sulfate and [3H]serine, total production and distribution of 35S-labeled proteoglycan into media (60–65%), pericellular (21–27%)
Rick T. Owens, William D. Wagner
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Abstract Proteoglycan production was examined in cultures of thioglycollate-elicited peritoneal macrophages obtained from White Carneau and Show Racer pigeons. Following a 24-h incubation in the presence of [35S]sulfate and [3H]serine, total production and distribution of 35S-labeled proteoglycan into media (60–65%), pericellular (21–27%)
Rick T. Owens, William D. Wagner
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Isolation, Purification, and Analysis of Chondroitin Sulfate Proteoglycans
2006Publisher Summary This chapter discusses widely applicable procedures for the purification and characterization of chondroitin sulfate proteoglycans (CSPGs), using several typical CSPG species as examples. The purification of CSPGs is an essential step to determine the structure and function of CSPGs.
Atsuhiko Oohira, Fumiko Matsui
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