Genomics and Histopathology in Interstitial Cystitis/Bladder Pain Syndrome
ABSTRACT Aims In April of 2025, a Global Consensus meeting on IC/BPS was held in Winston‐Salem, NC. The goal of this meeting was to establish global consensus in diagnostic criteria, phenotyping, treatment outcome assessment, and possible etiopathology in interstitial cystitis/bladder pain syndrome (IC/BPS).
Hannah Ruetten+4 more
wiley +1 more source
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
Fucosylated Chondroitin Sulfates from the Sea Cucumbers Paracaudina chilensis and Holothuria hilla: Structures and Anticoagulant Activity. [PDF]
Ustyuzhanina NE+7 more
europepmc +1 more source
Abstract Chondroitin sulfate proteoglycan 4 (CSPG4) is a promising target for melanoma immunotherapy, but its expression in benign melanocytic lesions and its diagnostic value remain unexplored. This study assessed CSPG4 expression in benign nevi (BN), dysplastic nevi (DN), and superficial spreading melanomas (SSM), comparing it with PRAME ...
Elias AT Koch+8 more
wiley +1 more source
Diverse reactivity of maleimides in polymer science and beyond
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick+2 more
wiley +1 more source
CHONDROITIN SULFATE CONCENTRATION AND PROTEIN-POLYSACCHARIDE COMPOSITION OF ARTICULAR CARTILAGE IN OSTEOARTHRITIS* [PDF]
Alfred Jay Bollet+2 more
openalex +1 more source
Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
The review presents a comprehensive overview of each component of lipid nanoparticles(LNPs)and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu+6 more
wiley +1 more source
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang+9 more
wiley +1 more source
SPECIFIC ADSORPTION OF METACHROMATIC COMPOUNDS OF CHONDROITIN SULFATE BY INSOLUBLE CALCIUM SALTS [PDF]
Medini Kanta Pal, Maxwell Schubert
openalex +1 more source
Targeting CA2 Perineuronal Nets Restores Recognition Memory and Theta Oscillations in Aged Mice
Targeting CA2 perineuronal nets restores social/non‐social recognition memory and theta oscillations in aged mice: Aged mice displayed deficits in both social and object recognition memory, which were accompanied by enhanced perineuronal nets (PNNs) density and reduced theta power in the dCA2 region.
Sonam Fathima Mehak+5 more
wiley +1 more source