Results 101 to 110 of about 7,722 (218)

Neurotrophic extracellular matrix proteins promote neuronal and iPSC astrocyte progenitor cell‐ and nano‐scale process extension for neural repair applications

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 585-601, April 2025.
The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor   +9 more
wiley   +1 more source

A Systematic Targeted Genetic Screen Identifies Proteins Involved in Cytoadherence of the Malaria Parasite P. falciparum

open access: yesMolecular Microbiology, Volume 123, Issue 4, Page 330-343, April 2025.
In silico workflow for selection of genes targeted in this study. We have identified a number of proteins involved in host cell modification by malaria parasites. Furthermore, we highlight a number of genes that appear to be essential for blood‐stage survival of these parasites.
Nina Küster   +4 more
wiley   +1 more source

Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of Borrelia burgdorferi Elp Proteins

open access: yesMolecular Microbiology, EarlyView.
A novel approach using the Pseudomonas syringae ice nucleation protein (INP) system to present Borrelia burgdorferi lipoproteins on the surface of Escherichia coli reveals conservation of complement inhibitory functions among uncharacterized OspE/F‐like leader peptide (Elp) proteins.
Nathan Hill   +10 more
wiley   +1 more source

FROM GENE TO STRUCTURE: Formation of Iduronic Acid in Dermatan Sulfate by Two DS-epimerases [PDF]

open access: yes, 2008
During embryonic development and adult life a wide range of cell behaviors such as differentiation, proliferation and migration are in effect to maintain tissue integrity and function.
Pacheco, Benny
core  

PD‐L1, PD‐1, and CTLA‐4 mRNA In Situ Expression by Canine Oral Melanoma Cells and Immune Cells of the Tumour Microenvironment

open access: yesVeterinary and Comparative Oncology, Volume 23, Issue 2, Page 141-151, June 2025.
ABSTRACT Canine oral melanoma (OM) exhibits poor prognosis and limited treatment options. The success of immune checkpoint inhibitors (ICIs) in human melanoma has driven interest in similar therapeutic approaches in the dog, although the immunosuppressive mechanisms adopted by canine OM remain unclear. This study aimed to evaluate the expression of the
Greta Foiani   +10 more
wiley   +1 more source

Chondroitin sulfates act as extracellular gating modifiers on voltage-dependent ion channels. [PDF]

open access: yes, 2008
Andrini, O   +5 more
core   +1 more source

Physical activity and joint health: Implications for knee osteoarthritis disease pathophysiology and mechanics

open access: yesExperimental Physiology, EarlyView.
Abstract Knee osteoarthritis is experienced by hundreds of millions of people worldwide and is a major cause of disability. Although enhancing physical activity levels and the participation in exercise programmes has been proved to improve the debilitating illness of osteoarthritis, many do not engage in recommended levels of physical activity.
Karl Morgan   +3 more
wiley   +1 more source

Histological Evaluation of Subcutaneous Tissue Reactions to a Novel Bilayer Polycaprolactone/Silk Fibroin/Strontium Carbonate Nanofibrous Membrane for Guided Bone Regeneration: A Study in Rabbits

open access: yesClinical and Experimental Dental Research, Volume 11, Issue 3, June 2025.
ABSTRACT Objectives The selection of appropriate biomaterial for guided bone regeneration is challenging. The blending of polymers is a simple method to retain their characteristics and to compensate for the drawbacks of each component. The release of Sr+2 (strontium) ions from the polycaprolactone/strontium carbonate (PCL/SrC) nanocomposite is the ...
Lida Kheiri   +4 more
wiley   +1 more source

Determinants of Weddellite Formation: Chondroitin Sulfates and Citrate Determine Weddellite Formation In Vitro [PDF]

open access: yes, 1996
In synthetic urine (SU), addition of oxalate tends to form monohydrates of calcium oxalate. However, addition of oxalate to natural urine preferably forms calcium oxalate dihydrate (COD). Urine apparently contains a determinant for COD formation.
Kim, Kookmin M.
core   +1 more source

Home - About - Disclaimer - Privacy